1198593-73-5Relevant academic research and scientific papers
Expedient synthesis of N-fused indoles: A C-F activation and C-H insertion approach
Fuchibe, Kohei,Kaneko, Tsukasa,Mori, Keiji,Akiyama, Takahiko
supporting information; experimental part, p. 8070 - 8073 (2010/02/27)
Easy does it: A wide range of N-fused indole skeletons, which are core structures of many biologically potent molecules, are successfully furnished by a niobiumcatalyzed C(sp3)-H insertion reaction (see picture). The precursors are readily prepared by a palladium-catalyzed amination reaction of bromotrifluorotoluenes with cyclic amines.
