1198774-75-2Relevant academic research and scientific papers
Enantioselective synthesis of planar-chiral phosphines with 1,n-dioxa[n]paracyclophane scaffold and their application as chiral ligands
Kanda, Kazumasa,Oshima, Shoya,Shizuno, Tsubasa,Hamanaka, Risa,Fukai, Miku,Shibata, Takanori
, p. 1355 - 1370 (2014)
A new family of chiral phosphines based on planar-chiral 1,n-dioxa[n]paracyclophane scaffold was created. They were synthesized with excellent enantioselectivity via asymmetric ortho-lithiation using sec-butyllithium and (-)-sparteine. These phosphines were used as chiral ligands in three reactions: Ag-catalyzed allylation of imines, Pd-catalyzed asymmetric Sonogashira coupling of diiodoparacyclophanes, and Pd-catalyzed asymmetric Suzuki-Miyaura coupling of tricarbonyl(η6-ortho-dichlorobenzene)chromium.
Enantioselective Ag-catalyzed allylation of aldimines
Naodovic, Marina,Wadamoto, Manabu,Yamamoto, Hisashi
experimental part, p. 5129 - 5131 (2010/01/03)
A highly enantioselective synthesis of homoallylic amines, using allyltrimethoxysilane under Ag1 catalytic conditions, has been developed. Among the chiral ligands investigated, a remarkable difference in the resulting Ag1 complexes
