119895-91-9Relevant articles and documents
The Potential of Carbocyclic Nucleosides for the Treatment of AIDS: Synthesis of Carbocyclic 6'-Fluoro-2',3'-dideoxythymidine
Coe, Diane M.,Parry, David M.,Roberts, Stanley M.,Storer, Richard
, p. 2373 - 2378 (2007/10/02)
The carbocyclic nucleoside 4 and the corresponding triphosphate 5 were prepared from cyclopent-2-enylmethanol 6 in 8 and 10 steps respectively.The key step in the synthesis is the reaction of the azido alcohol 9 with diethylaminosulphur trifluoride: parti