137709-64-9Relevant academic research and scientific papers
The Potential of Carbocyclic Nucleosides for the Treatment of AIDS: Synthesis of Carbocyclic 6'-Fluoro-2',3'-dideoxythymidine
Coe, Diane M.,Parry, David M.,Roberts, Stanley M.,Storer, Richard
, p. 2373 - 2378 (2007/10/02)
The carbocyclic nucleoside 4 and the corresponding triphosphate 5 were prepared from cyclopent-2-enylmethanol 6 in 8 and 10 steps respectively.The key step in the synthesis is the reaction of the azido alcohol 9 with diethylaminosulphur trifluoride: parti
Synthesis of Compounds active against HIV. Part 2. Preparation of some 2',3'-Dideoxy-6'-fluorocarbocyclic Nucleosides
Coe, Diane M.,Myers, Peter L.,Parry, David M.,Roberts, Stanley M.,Storer, Richard
, p. 151 - 153 (2007/10/02)
A series of 2',3'-dideoxy-6'-fluorocarbocyclic nucleosides have been prepared and tested for activity against HIV; compound (20) showed weak antiviral activity.
