119910-72-4

Basic information

• Product Name: 1,2,3,3aα,4α,6,7,8,8aβ,8bα-decahydro-2-phenyl-4-(2-pyridyl)pyrrolo<3,4-a>pyrrolizine-1,3-dione
• CAS NO: 119910-72-4
• Molecular Weight: 333.39
• Mol File: 119910-72-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2,3,3aα,4α,6,7,8,8aβ,8bα-decahydro-2-phenyl-4-(2-pyridyl)pyrrolo<3,4-a>pyrrolizine-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,3aα,4α,6,7,8,8aβ,8bα-decahydro-2-phenyl-4-(2-pyridyl)pyrrolo<3,4-a>pyrrolizine-1,3-dione(119910-72-4)
• EPA Substance Registry System: 1,2,3,3aα,4α,6,7,8,8aβ,8bα-decahydro-2-phenyl-4-(2-pyridyl)pyrrolo<3,4-a>pyrrolizine-1,3-dione(119910-72-4)

Safety Data

• Hazardous Substances Data: 119910-72-4(Hazardous Substances Data)

Upstream product

• 1121-60-4 pyridine-2-carbaldehyde 
• 941-69-5 N-phenyl-maleimide 
• 609-36-9 rac-Pro-OH 

Relevant articles and documents

X=Y-ZH SYSTEMS AS POTENTIAL 1,3-DIPOLES. PART 11. STEREOCHEMISTRY OF 1,3-DIPOLES GENERATED BY THE DECARBOXYLATIVE ROUTE TO AZOMETHINE YLIDES

The decarboxylative reaction of aryl aldehydes with cyclic secondary α-amino acids or primary α-amino acids in the presence of N-methyl- or N-phenyl-maleimide leads, via an intermediate azomethine ylide, to mixtures of bicyclic pyrrolidine cycloadducts in good yield.Cyclic secondary α-amino acids, where the carboxylic group is non-benzylic, give cycloadducts arising from a stereospecifically generated anti-dipole.Acyclic α-amino acids, and cyclic secondary α-amino acids with the carboxylic group located at a benzylic site, give rise to cycloadducts derived from both anti- and syn-configurations of the intermediate azomethine ylides.The reactions show little discrimination between endo- and exo-transition states for the cycloadditions.