1199246-17-7Relevant articles and documents
Total synthesis of polyrhacitides A and B by Use of an iterative strategy for the stereoselective synthesis of 1,3-Polyol arrays
Menz, Helge,Kirsch, Stefan F.
, p. 5634 - 5637 (2009)
[Chemical Equation Presented] The first total syntheses of polyrhacitides A and B, secondary metabolites from Chinese medicinal ants, were accomplished via an iterative approach to the 1,3-polyol motif. For the construction of all stereogenic centers, the
The use of COP-OAc in the catalyst-controlled syntheses of 1,3-polyols
Kirsch, Stefan F.,Klahn, Philipp,Menz, Helge
, p. 3592 - 3603 (2011/12/21)
An iterative strategy to the 1,3-polyol motif is described. The use of the catalytic asymmetric Overman esterification for the construction of all stereogenic centers is broadly examined as are the sequences to extend the developing polyol chain. The iterative strategies are applied to the total syntheses of rugulactone and polyrhacitides A and B. 1 Introduction 2 Results and Discussion 2.1 Chain Elongation via RCM (Cycle A) 2.2 Total Synthesis of Rugulactone 2.3 Chain Elongation via Ando Olefination (Cycle B) and Total Syntheses of Polyrhacitides A and B 2.4 Useful Variants 3 Conclusions. Georg Thieme Verlag Stuttgart. New York.
