119934-20-2

Upstream product

• 90256-78-3 7-Chlor-1-methyl-5-phenyl-2-thioxo-2,3-dihydro-1H-1,3,4-benzotriazepin 
• 111-42-2 2,2'-iminobis[ethanol] 

Downstream Products

• 119934-19-9 (5-Chlor-2-methylaminobenzophenon)-4-(2-hydroxyethyl)thiosemicarbazon 
• 90256-78-3 7-Chlor-1-methyl-5-phenyl-2-thioxo-2,3-dihydro-1H-1,3,4-benzotriazepin 

Relevant academic research and scientific papers

Synthesis and biological activity of 5-phenyl-1,3,4-benzotriazepines. 14. The reactions of 2-thioxo-5-phenyl-1,3,4-benzotriazepines

The interaction of 2-aminoethanol and 2-thioxo-5-phenyl-1,3,4-benzotriazepines in abs. dioxane under refluxing conditions was investigated. Depending on the substitution of the triazepine ring several products are formed. The S-N-exchange to form the corresponding 2-(2-hydroxyethyl)-amino derivatives only takes place if the nitrogen atoms of the heterocycle are unsubstituted.