119943-46-3 Usage
Uses
Used in Pharmaceutical Applications:
(7β)-7-O-methylmorroniside is used as a therapeutic agent for the treatment of conditions like Alzheimer's disease, diabetes, and cardiovascular diseases. Its antioxidant properties make it a promising candidate for developing new treatments to combat oxidative stress-related disorders.
Used in Neurodegenerative Disease Treatment:
In the field of neurology, (7β)-7-O-methylmorroniside is used as a potential treatment for neurodegenerative diseases due to its demonstrated protective effects on the nervous system.
Used in Herbal Medicine:
(7β)-7-O-methylmorroniside is also utilized in the herbal medicine industry, where it is extracted from plants like mulberry and Cornus officinalis for its various health benefits, including its anti-inflammatory and neuroprotective effects.
Check Digit Verification of cas no
The CAS Registry Mumber 119943-46-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,9,4 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 119943-46:
(8*1)+(7*1)+(6*9)+(5*9)+(4*4)+(3*3)+(2*4)+(1*6)=153
153 % 10 = 3
So 119943-46-3 is a valid CAS Registry Number.
119943-46-3Relevant academic research and scientific papers
Synthesis and promotion of the osteoblast proliferation effect of morroniside derivatives
Han, Hua,Li, ZhengQing,Qu, Na,Chen, Si,Dong, PeiLiang
, (2018/06/15)
Sambucus williamsii Hance has been used in fractures for thousands of years, but research on its active components, such as morroniside, until now had not been carried out. In this study, morroniside was taken as the leading compound, and fourteen derivatives were synthesized. The promotion of osteoblast proliferation effect of the derivatives was evaluated on MC3T3-E1 cells. Five derivatives (2, 3, 4, 5, and 14) showed a good proliferation effect on MC3T3-E1 cells, and their promoted expression effects on OC (Osteocalcin) and ALP (Alkaline phosphatase) in MC3T3-E1 cells were measured. Compound 3 was shown to have the strongest proliferation effect (EC50 = 14.78 ± 1.17 μg/mL) and to significantly promote the expression of OC and ALP.
