1199773-75-5

Basic information

• Product Name: 3-Cyano-piperidine hydroc...
• Synonyms: 3-Piperidinecarbonitrile, hydrochloride (1:1)
• CAS NO: 1199773-75-5
• Molecular Formula: C6H11ClN2
• Molecular Weight: 146.61794
• Mol File: 1199773-75-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 3-Cyano-piperidine hydroc...(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyano-piperidine hydroc...(1199773-75-5)
• EPA Substance Registry System: 3-Cyano-piperidine hydroc...(1199773-75-5)

Safety Data

• Hazardous Substances Data: 1199773-75-5(Hazardous Substances Data)

Usage

General Description

3-Cyano-piperidine hydrochloride is a chemical compound that is used in the pharmaceutical industry for the synthesis of various drugs and medicines. It is a derivative of piperidine and contains a cyano group, which makes it useful for reactions that involve amino groups. 3-Cyano-piperidine hydroc... is often used as an intermediate in the production of antihistamines, antipsychotic drugs, and other pharmaceuticals. 3-Cyano-piperidine hydrochloride is known for its versatile properties and is used in organic synthesis to create complex molecules with therapeutic potential.

Upstream product

• 91419-53-3 (+/-)-2-N-tert-butoxycabonylpiperidine-3-carbonitrile 
• 88495-54-9 (3S)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid 
• 88466-77-7 (S)-3-carbamoyl-piperidine-1-carboxylic acid tert-butyl ester 
• 915226-39-0 (S)-3-carbamoyl-piperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 915226-65-2 (S)-1-(4-fluoro-benzoyl)-N-hydroxy-piperidine-3-carboxamidine 

Relevant articles and documents

Carbazole inhibitors of histamine receptors for the treatment of disease

The present invention relates to carbazole compounds, pharmaceutical compositions comprising them, and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.

PHENYL-3-{ (3- (1H- PYRROL- 2 -YL) - [1 , 2 , 4] 0XADIAZ0L-5-YL] PIPERIDIN-1-YL}-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention provides new compounds of formula (I) as positive allosteric modulators of metabotropic receptors - subtype 5 ("mGluR5") which are useful for the treatment or prevention of central nervous system disorders such as for example, cognitive decline, both positive and negative symptoms in schizophrenia as well as other central or peripheral nervous system disorders in which the mGluR5 subtype of glutamate metabotropic receptor is involved. The invention is also directed to pharmaceutical compounds and compositions in the prevention or treatment of such diseases in which mGluKi is involved. W represents (C4-C7)cycloalkyl, (C3-C7)heterocycloalkyl , (C3-C7)heterocycloalkyl-(C1-C3)alkyl or (C3-C7)heterocycloalkenyl ring; represents a (C5-C7)heteroeycloalkyl, (C5-C7)heterocycloalkeiiyl ring or a heteroaryl group of formula (a), (b), (c), (d), (e), (f), (g), (i). Q denotes a cycloalkyl, an aryl or heteroaryl group of formula (j), (k), (l), (m), (n). A is azo -N=N-, ethyl, ethenyl, ethynyl, -NR8C(=O)-, -NR8C(=O)-O-, -NR8C(=O)-NR9, NR8S(=O)2-, -C(=O)NR8-, -O-C(=O)NR8-, -S-, -S(=O)-, -S(=O)2-, -S(C=O)2NR8-, -C(=0)-0-, -0-C(=0)-, -C(=NR8)NR9-, C(C=NOR8)NR9- , -NR8C(=NOR9)-, =N-0-, -0-N=CH- or a group aryl or heteroaryl of formula, (o), (p), (q), (r), (s), (t), (u), (v), (w), (x). The other substituents are defined in the claims.