1200115-87-2Relevant academic research and scientific papers
Design, synthesis and evaluation of novel oxazaphosphorine prodrugs of 9-(2-phosphonomethoxyethyl)adenine (PMEA, adefovir) as potent HBV inhibitors
Lu, Peng,Liu, Jiangxia,Wang, Yuya,Chen, Xiaoyan,Yang, Yushe,Ji, Ruyun
, p. 6918 - 6921 (2009)
A series of novel oxazaphosphorine prodrugs of 9-(2-phosphonomethoxyethyl)adenine (PMEA, adefovir) were synthesized and their anti-hepatitis B virus (HBV) activity was evaluated in HepG2 2.2.15 cells, with adefovir dipivoxil as a reference drug. In the ce
