120029-99-4Relevant academic research and scientific papers
Carbohydrates as Chiral Templates: Stereoselective Strecker Synthesis of D-α-Amino Nitriles and Acids Using O-Pivaloylated D-Galactosylamine as the Auxiliary
Kunz, Horst,Sager, Wilfried,Schanzenbach, Dirk,Decker, Mathias
, p. 649 - 654 (2007/10/02)
The asymmetric synthesis of N-galactosyl D-α-amino nitriles is accomplished by application of 2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosylamine (4) as the stereodifferentiating template in Strecker reactions.Aldimines 6 derived from 4 and aromatic or ali
REVERSAL OF ASYMMETRIC INDUCTION IN STEREOSELECTIVE STRECKER SYNTHESIS ON GALACTOSYL AMINE AS THE CHIRAL MATRIX
Kunz, Horst,Sager, Wilfried,Pfrengle, Waldemar,Schanzenbach, Dirk
, p. 4397 - 4400 (2007/10/02)
The reversal of the direction of asymmetric induction in Lewis acid catalyzed Strecker synthesis using the 2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl amine 1 is described.In isopropanol or tetrahydrofuran 1 had given (R)-diastereomers of the correspond
