120040-42-8

Basic information

• Product Name: 2-AMINO-6-BROMOPYRIDO[2,3-D]PYRIMIDIN-4(3H)-ONE
• Synonyms: 2-AMINO-6-BROMOPYRIDO[2,3-D]PYRIMIDIN-4(3H)-ONE;2-aMino-6-broMo-3H,4H-pyrido[2,3-d]pyriMidin-4-one;2-amino-6-bromopyrido[2,3-d]pyrimidin-4(1H)-one;2-Amino-6-bromopyrido[2,3-d]pyrimidin-4(3H);Pyrido[2,3-d]pyrimidin-4(1H)-one, 2-amino-6-bromo-
• CAS NO: 120040-42-8
• Molecular Formula: C₇H₅BrN₄O
• Molecular Weight: 241.05
• Mol File: 120040-42-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 508.9 °C at 760 mmHg
• Flash Point: 261.6 °C
• Appearance: /
• Density: 2.006 g/cm³
• Vapor Pressure: 5.6E-11mmHg at 25°C
• Refractive Index: 1.817
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -0.35±0.20(Predicted)
• CAS DataBase Reference: 2-AMINO-6-BROMOPYRIDO[2,3-D]PYRIMIDIN-4(3H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-6-BROMOPYRIDO[2,3-D]PYRIMIDIN-4(3H)-ONE(120040-42-8)
• EPA Substance Registry System: 2-AMINO-6-BROMOPYRIDO[2,3-D]PYRIMIDIN-4(3H)-ONE(120040-42-8)

Safety Data

• Hazardous Substances Data: 120040-42-8(Hazardous Substances Data)

Usage

General Description

2-AMINO-6-BROMOPYRIDO[2,3-D]PYRIMIDIN-4(3H)-ONE is a chemical compound with the molecular formula C7H5BrN4O. It is a pyrido pyrimidinone derivative with a bromine atom attached to the 6th position of the pyridine ring. 2-AMINO-6-BROMOPYRIDO[2,3-D]PYRIMIDIN-4(3H)-ONE is a heterocyclic aromatic organic compound that contains both a pyridine and pyrimidine ring. It can be used as a building block in organic synthesis and may have potential pharmaceutical or biological applications. The specific properties and uses of 2-AMINO-6-BROMOPYRIDO[2,3-D]PYRIMIDIN-4(3H)-ONE will depend on further research and development.

InChI:InChI=1/C7H5BrN4O/c8-3-1-4-5(10-2-3)11-7(9)12-6(4)13/h1-2H,(H3,9,10,11,12,13)

Upstream product

• 100643-27-4 2,6-diamino-3H-pyrimidin-4-one 
• 2065-75-0 2-Bromo-malonaldehyde 
• 152941-64-5 6-bromo-2-pivaloylamino-4<1'-(1,2,4-triazolyl)>-5-deazapteridine 
• 116387-22-5 2-pivaloylamino-6-bromo-4(3H)-pyrido[2,3-d]pyrimidinone 
• 152941-66-7 6-bromo-4-ethoxy-2-pivaloylamino-5-deazapteridine 
• 6020-53-7 2,6-diamino-4(3H)-pyrimidinone monohydrate 

Downstream Products

• 120040-43-9 2-pivaloyl-6-styryl-5-deazapterin 
• 155690-84-9 4-<2-(2-Amino-1,4,5,6,7,8-hexahydro-4-oxopyrido<2,3-d>pyrimidin-6-yl)ethyl>benzonic acid 
• 95693-76-8 (6RS)-5,10-dideaza-5,6,7,8-tetrahydrofolic acid 
• 185814-12-4 (6RS)-methyl 4-[2-(2-pivaloylamino-4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-6-yl)ethyl]benzoate 

Relevant articles and documents

Stereoselective process for the synthesis of chiral garft compounds and intermediates

The present invention describes a stereoselective preparation of derivatives and precursors of molecules having formula 1: Method of preparing the compounds, intermediates and derivatives are described. The methods described herein allow the preparation o

PROTECTION AND DEPROTECTION OF FUSED 2-AMINO-4(3H)PYRIMIDONES: CONVERSION OF PTERINS AND 5-DEAZAPTERINS TO 2,4-DIAMINO DERIVATIVES

5-Deazapterins and pterins are readily converted to their 4-deoxy-4-amino derivatives (a lactam-to-amidine conversion) by reaction with 4-chlorophenyl phosphorodichloridate and 1,2,4-triazole to give intermediate 4- derivatives, followed by reaction with aqueous ammonia.Some anomalous results obtained by application of the Mitsunobu reaction (normally a lactam-to-lactim ether conversion) to 5-deazapterins are detailed.