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100643-27-4 Usage

General Description

4-Pyrimidinol, 2,6-diamino- (9CI) is a chemical compound with the molecular formula C4H6N4O. It is a derivative of pyrimidinol, which is a heterocyclic compound that contains both nitrogen and oxygen atoms in its ring structure. 4-Pyrimidinol, 2,6-diamino- (9CI) has two amino groups and a hydroxyl group attached to the pyrimidine ring. 4-Pyrimidinol, 2,6-diamino- (9CI) has potential applications in the pharmaceutical industry, particularly in the development of new drugs and therapies. Its chemical properties and structure make it a subject of interest for further research and exploration in the field of medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 100643-27-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,6,4 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 100643-27:
74 % 10 = 4
So 100643-27-4 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017


1.1 GHS Product identifier

Product name 2,4-diamino-6(1H)-pyrimidone

1.2 Other means of identification

Product number -
Other names 2-[(benzyloxy)methyl]oxirane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100643-27-4 SDS

100643-27-4Relevant articles and documents

Green Microwave-assisted Multicomponent Route to the Formation of 5,8-Dihydropyrido[2,3-d]pyrimidine Skeleton in Aqueous Media

Saraev, Vyacheslav E.,Zviagin, Ievgen M.,Melik-Oganjanyan, Rafael G.,Sen'ko, Yulia V.,Desenko, Sergey M.,Chebanov, Valentin A.

, p. 318 - 324 (2017)

Three-component synthesis of 5-substituted 6-acetyl-2-amino-7-methyl-5,8-dihydropyrido[2,3-d]pyrimidines was brought to facile energy-efficient and environmental-friendly conditions using multicomponent reaction, microwave field as an activation method and hot water as a solvent. A series of the target compounds was synthesized using the developed procedure.

Preparation methods of 2,4-diamido-5-nitroso-6-hydroxypyridine and guanine


Paragraph 0053; 0054; 0055; 0056; 0057; 0063; 0064-0066, (2018/10/19)

The invention discloses a preparation method of 2,4-diamido-5-nitroso-6-hydroxypyridine. The preparation method comprises the following steps: (1) in a sodium methoxide methanol solution, carrying outa ring-closure reaction between methyl cyanoacetate and guanidine salt; (2) adding recycled absolute methanol to be diluted, filtering and recycling byproduct sodium nitrate; (3) concentrating a filter liquor, and recycling absolute methanol; (4) adding water to destroy excessive sodium methoxide, concentrating and recycling water-containing methyl alcohol; (5) in a diluted methane acid solution,carrying out a nitrosation reaction among an obtained concentrate, sodium nitrite and a nitrosation mother liquor; (6) after the reaction ends, carrying out cooling crystallization, filtering, takinga filter liquor as the nitrosation mother liquor to be used indiscriminately, and drying an obtained filter cake to obtain the 2,4-diamido-5-nitroso-6-hydroxypyridine. According to the preparation method, indiscriminate use of the nitrosation mother liquor and recycling of sodium nitrate and methyl alcohol are realized, and simultaneously the diluted methane acid solution is used for replacing concentrated sulfuric acid used, in the prior art, to carry out the nitrosation reaction, so that the recycling of a solvent and a reagent is facilitated, and the displacement of waste water is reduced.

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