1200436-16-3Relevant academic research and scientific papers
Enantioselective Synthesis of Chiral Phosphonates via Rh/f-spiroPhos Catalyzed Asymmetric Hydrogenation of β,β-Disubstituted Unsaturated Phosphonates
Wang, Chaoqiong,Xie, Fang,Guo, Qianling,Xie, Chaochao,Zi, Guofu,Ye, Weiping,Zhou, Zhangtao,Hou, Guohua,Zhang, Zhanbin
, p. 12034 - 12045 (2021)
The first asymmetric hydrogenation of β,β-diaryl unsaturated phosphonates has been realized for synthesis of β,β-diaryl chiral phosphonates with excellent enantioselectivities (up to 99.9% ee) catalyzed by the Rh-(R,R)-f-spiroPhos complex. Furthermore, this catalyst also exhibits comparably excellent performance for β-aryl-β-alkyl unsaturated phosphonates providing the corresponding chiral phosphonates with up to 99.9% ee values. This methodology provides a straightforward access to asymmetric synthesis of chiral phosphonates.
Inverting External Asymmetric Induction via Selective Energy Transfer Catalysis: A Strategy to β-Chiral Phosphonate Antipodes
Onneken, Carina,Bussmann, Kathrin,Gilmour, Ryan
supporting information, p. 330 - 334 (2019/12/11)
Enantiodivergent, catalytic reduction of activated alkenes relays stereochemical information encoded in the antipodal chiral catalysts to the pro-chiral substrate. Although powerful, the strategy remains vulnerable to costs and availability of sourcing bo
Enantioselective synthesis of optically active alkylphosphonates via Rh-catalyzed asymmetric hydrogenation of β-substituted α,β- unsaturated phosphonates
Duan, Zheng-Chao,Wang, Lian-Zhi,Song, Xin-Jian,Hu, Xiang-Ping,Zheng, Zhuo
experimental part, p. 508 - 514 (2012/08/07)
The Rh-catalyzed asymmetric hydrogenation of β-substituted α,β-unsaturated phosphonates using (Sc,S p)-WalPhos as the chiral ligand is reported, in which a wide range of optically active β-substituted alkylphosphonates were obtained
