1200507-85-2Relevant academic research and scientific papers
Scaffold-based design and synthesis of potent N-type calcium channel blockers
Zamponi, Gerald W.,Feng, Zhong-Ping,Zhang, Lingyun,Pajouhesh, Hossein,Ding, Yanbing,Belardetti, Francesco,Pajouhesh, Hassan,Dolphin, David,Mitscher, Lester A.,Snutch, Terrance P.
scheme or table, p. 6467 - 6472 (2010/04/30)
The therapeutic agents flunarizine and lomerizine exhibit inhibitory activities against a variety of ion channels and neurotransmitter receptors. We have optimized their scaffolds to obtain more selective N-type calcium channel blockers. During this optim
