120067-47-2Relevant academic research and scientific papers
(1H-azol-1-ylmethyl)substituted quinoline derivatives
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, (2008/06/13)
(1H-azol-1-ylmethyl)substituted quinoline derivatives, compositions containing the same, and methods of treating mammals suffering from disorders which are characterized by an increase proliferation and/or abnormal differentation of epithelial tissues.
3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase
Martinez,Walker,Hirschfeld,Bruno,Yang,Maloney
, p. 620 - 628 (2007/10/02)
A series of 1H-imidazol-1-yl- and 3-pyridyl-substituted 3,4- dihydroquinolin-2(1H)-ones was designed and synthesized as combined inhibitors of thromboxane (TXA2) synthase and cAMP phosphodiesterase (PDE) in human blood platelets. A number of st
Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors
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, (2008/06/13)
The invention concerns a method of inhibiting both thromboxane synthetase and cyclic-AMP phosphodiesterase in a mammal having a disease characterized by elevated thromboxane levels or an imbalance of prostacyclin/thromboxane levels with a compound of the
