120091-95-4

Upstream product

• 38103-07-0 methyl 3-chloro-2,4-dihydroxy-6-methylbenzoate 
• 77-78-1 dimethyl sulfate 
• 520-43-4 2-hydroxy-4-methoxy-6-methyl-benzoic acid methyl ester 
• 128855-50-5 methyl 3-chloro-2,4-dimethoxy-6-methylbenzoate 

Downstream Products

• 128855-55-0 2,2',6'-tribenzyloxy-5-bromo-3-chloro-4-methoxy-4',6'-dimethylbenzophenone 
• 128855-54-9 2,2',4'-tribenzyloxy-5-bromo-3-chloro-4-methoxy-6,6'-dimethylbenzophenone 
• 128855-56-1 5-bromo-3-chloro-2,2',4'-trihydroxy-4-methoxy-6,6'-dimethylbenzophenone 
• 128855-53-8 2-benzyloxy-5-bromo-3-chloro-4-methoxy-6-methylbenzoic acid 
• 128855-52-7 2-Benzyloxy-5-bromo-3-chloro-4-methoxy-6-methyl-benzoic acid methyl ester 
• 128855-51-6 methyl 2-benzyloxy-3-chloro-4-methoxy-6-methylbenzoate 

Relevant academic research and scientific papers

2,2,6,6-Tetramethylpiperidine-catalyzed, ortho-selective chlorination of phenols by sulfuryl chloride

2,2,6,6-Tetramethylpiperidine (TMP)-catalyzed (1- 10%) chlorinations of phenols by SO2Cl2 in aromatic solvents are more ortho selective than with primary and less hindered secondary amine catalysts. Ortho-selective chlorination is successful even with electron deficient phenols such as 2-hydroxybenzaldehyde and 2'- hydroxyacetophenone. Notably, ortho selectivity increases with the reaction temperature. On the other hand, tetraalkylammonium chloride-catalyzed chlorinations are moderately para selective.

The Structure of the Lichen Depsidones Fulgidin and Isofulgidin

The depsidone isofulgidin (1) (2,4,7-trichloro-3-hydroxy-8-methoxy-1,6-dimethyl-11H-dibenzo-dioxepin-11-one), has been isolated from the lichen Rinodina dissa together with atranorin and diploicin (3).Isofulgidin (1) has also been detected in th