1201-41-8

Upstream product

• 75-21-8 oxirane 
• 4478-10-8 2-bromo-1-isopropyl-4-methyl-benzene 
• 181129-75-9 ethyl 2-isopropyl-5-methylphenylacetate 
• 89-78-1 menthol 
• 31041-97-1 ethyl 2-isopropyl-5-methyl-1-hydroxycyclohexane-1-acetate 
• 10458-14-7 Menthone 

Downstream Products

• 1198-90-9 1-Methyl-3-ethyl-4-isopropyl-benzol 
• 181129-92-0 1-[2-(2-Isopropyl-5-methyl-phenyl)-ethyl]-4-methyl-2-oxo-cyclohexanecarboxylic acid ethyl ester 
• 1201-40-7 β-(2-isopropyl-5-methylphenyl)ethyl bromide 

Relevant academic research and scientific papers

Synthesis of substituted chrysenes and phenanthrenes

3-Methylchrysene (9a), 2, 3, 9-trimethylchrysene (9b), 2, 6-dimethylphenanthrene (16a) and 1-isopropyl-4,6-dimethylphenanthrene (16b) have been synthesised in the following steps. β-(1-Naphthyl)ethyl bromide (6a), β-(6,7-dimethyl-1-naphthyl)ethyl bromide (6b), β-(3-methylphenyl)ethyl bromide (13a) and β-(2-isopropyl-5-methylphenyl)ethyl bromide (13b) are separately condensed with potassium salt of 1-carbethoxy-4-methylcyclohexane-2-one (1) to give respectively 7a, 7b, 14a and 14b. PPA cyclisation of 7a and 7b affords 8a and 8b while 14a affords 15a and 14b gives a mixture of 15b and 15c. Aromatisation of 8a and 8b leads to 9a and 9b and that of 15a gives 16a while 15b and 15c both produce 16b. The structures assigned are consistent with their spectral data.