1201-60-1

Basic information

• Product Name: 1-(1,2-dibromopropyl)-4-methoxybenzene
• CAS NO: 1201-60-1
• Molecular Formula: C₁₀H₁₂Br₂O
• Molecular Weight: 308.0097
• Mol File: 1201-60-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 311.2°C at 760 mmHg
• Flash Point: 125.4°C
• Density: 1.618g/cm³
• Vapor Pressure: 0.00105mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 1-(1,2-dibromopropyl)-4-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1,2-dibromopropyl)-4-methoxybenzene(1201-60-1)
• EPA Substance Registry System: 1-(1,2-dibromopropyl)-4-methoxybenzene(1201-60-1)

Safety Data

• Hazardous Substances Data: 1201-60-1(Hazardous Substances Data)

Usage

General Description

1-(1,2-dibromopropyl)-4-methoxybenzene, also known as dibromopropyl methoxybenzene, is a chemical compound that belongs to the class of organobromine compounds. It is derived from propyl and methoxybenzene, and is characterized by its molecular formula C10H11Br2O and a molecular weight of 296.998 g/mol. 1-(1,2-dibromopropyl)-4-methoxybenzene is commonly used in organic synthesis and chemical research as a reagent for forming carbon-carbon and carbon-oxygen bonds. It is also utilized in the production of pharmaceuticals and agrochemicals. Furthermore, 1-(1,2-dibromopropyl)-4-methoxybenzene is considered a potential mutagen, and precautions should be taken when handling and disposing of it.

Upstream product

• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 
• 60-29-7 diethyl ether 
• 7726-95-6 bromine 
• 104-46-1 anethole 
• 91-16-7 1,2-dimethoxybenzene 

Downstream Products

• 127193-12-8 2-bromo-1-methoxy-1-(4-methoxyphenyl)-propane 
• 70812-94-1 1-(1-ethoxy-propenyl)-4-methoxy-benzene 
• 857591-12-9 1-(1-ethoxy-2-bromo-propyl)-4-methoxy-benzene 
• 97424-75-4 1,2-diacetoxy-1-(4-methoxy-phenyl)-propane 
• 19967-57-8 bromo-2 propanal 
• 4374-35-0 α-bromoethyl 3-bromo-4-methoxyphenyl ketone 
• 252058-33-6 2-(4-methoxyphenyl)propanal 
• 21086-33-9 2-bromo-1-(4-methoxyphenyl)-1-propanone 
• 256385-72-5 1-(1-hydroxy-2-bromopropyl)-4-methoxybenzene 
• 51410-48-1 1-(4-methoxy-phenyl)-propane-1,2-diol 
• 104-94-9 4-methoxy-aniline 
• 121-97-1 4-Methoxypropiophenone 
• 80167-17-5 methyl-[4-(2-bromo-propenyl)-phenyl]-ether 
• 645-49-8 cis-stilben 

Relevant articles and documents

Cis-Dioxomolybdenum(VI) complexes with unsymmetric linear tetradentate ligands: Syntheses, structures and bromoperoxidase activities

Reactions of [MoO2(acetylacetonate)2], 2-((2-(2-hydroxyethylamino)ethylamino)methyl)-4-R-phenols (H2Ln, n = 1-5 for R = H, Me, OMe, Cl and Br, respectively) and KOH in 1:1:2 mole ratio in methanol afford a series of complexes having the general formula cis-[MoO2(Ln)] (1, 2, 3, 4, 5) in 81-86% yields. The complexes have been characterized using elemental analysis, spectroscopy (infrared, UV-visible, and 1H NMR, 13C NMR and 13C-DEPT NMR) and electrochemical measurements. The molecular structures of 1, 2, 3, 4 have been determined using single-crystal X-ray crystallography. In each of 1, 2, 3, 4, the ONNO-donor 6,5,5-membered fused chelate rings forming (Ln)2- and the two mutually cis oxo groups assemble a distorted octahedral N2O4 coordination sphere around the metal centre. In the crystal lattice, each of 1, 2, 3, 4 forms a one-dimensional infinite chain structure via intermolecular N-H...O hydrogen bonding interactions. In cyclic voltammograms, the diamagnetic complexes display an irreversible metal-centred reduction in the potential range -0.73 to -0.88 V (vs Ag/AgCl). The physicochemical data are consistent with a very similar gross molecular structure for all of 1, 2, 3, 4, 5. All the complexes exhibit decent bromoperoxidase activities and are also able to effectively catalyse benzoin and methyl(phenyl)sulfide oxidation reactions.

Samarium triflate-catalyzed halogen-promoted Friedel-Crafts alkylation with alkenes

A versatile and efficient halogen-promoted highly regio- and stereoselective Friedel - Crafts (F-C) alkylation with alkenes has been developed with use of easily available and inexpensive NBS or I2 as the efficient halogen sources. Lewis acids, in particular metal triflates, are found to be effective catalysts for this halogen-promoted F-C alkylation. Among these, Sm(OTf)3 was the best catalyst. Electron-rich arenes smoothly underwent F-C alkylation with a variety of alkenes including α,β-unsaturated carbonyl compounds.