120107-85-9

Basic information

• Product Name: 3-(1H-IMIDAZOL-1-YLMETHYL)ANILINE
• Synonyms: TIMTEC-BB SBB007514;3-(1H-IMIDAZOL-1-YLMETHYL)ANILINE;3-(1H-Imidazol-1-ylmethyl)aniline 97%;[3-(1H-imidazol-1-ylmethyl)phenyl]amine dihydrochloride;3-(1H-imidazol-1-ylmethyl)Benzenamine;3-Imidazol-1-ylmethyl-phenylamine;3-(1H-imidazol-1-ylmethyl)aniline(SALTDATA: 2HCl);1-(3-Aminobenzyl)-1H-imidazole
• CAS NO: 120107-85-9
• Molecular Formula: C₁₀H₁₁N₃
• Molecular Weight: 173.21
• Mol File: 120107-85-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 72 °C
• Boiling Point: 392.8°Cat760mmHg
• Flash Point: 191.4°C
• Appearance: /
• Density: 1.16g/cm³
• Vapor Pressure: 2.23E-06mmHg at 25°C
• Refractive Index: 1.622
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-(1H-IMIDAZOL-1-YLMETHYL)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1H-IMIDAZOL-1-YLMETHYL)ANILINE(120107-85-9)
• EPA Substance Registry System: 3-(1H-IMIDAZOL-1-YLMETHYL)ANILINE(120107-85-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 120107-85-9(Hazardous Substances Data)

Usage

Uses

3-(1H-Imidazol-1-ylmethyl)aniline functions as a selective aldosterone synthase inhibitors. Research on antibacterial and antifungal agents (benzenamine derivatives).

InChI:InChI=1/C10H11N3/c11-10-3-1-2-9(6-10)7-13-5-4-12-8-13/h1-6,8H,7,11H2

Upstream product

• 3958-57-4 1-bromomethyl-3-nitrobenzene 
• 56643-75-5 1-(3-nitro-benzyl)-1H-imidazole 
• 99-08-1 1-methyl-3-nitrobenzene 
• 5587-42-8 imidazolyl sodium 
• 892393-24-7 1-(1H-imidazol-1-yl)-1-[3-[(tert-butoxycarbonyl)amino]phenyl]-methane 

Downstream Products

• 120107-87-1 (3-Imidazol-1-ylmethyl-phenyl)-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-amine 
• 120107-90-6 [1-(2,4-Dichloro-phenyl)-meth-(E)-ylidene]-(3-imidazol-1-ylmethyl-phenyl)-amine 
• 120108-17-0 4-Chloro-N-(3-imidazol-1-ylmethyl-phenyl)-benzamide 
• 120108-13-6 N-(3-Imidazol-1-ylmethyl-phenyl)-3-nitro-benzamide 
• 1138471-71-2 (7-chloroquinolin-4-yl)(3-imidazol-1-ylmethylphenyl)amine 
• 120123-73-1 (3-Imidazol-1-ylmethyl-phenyl)-[1-(4-nitro-phenyl)-meth-(E)-ylidene]-amine 
• 120107-91-7 (3-Imidazol-1-ylmethyl-phenyl)-[1-(3-nitro-phenyl)-meth-(E)-ylidene]-amine 
• 120107-86-0 [1-(2-Chloro-phenyl)-meth-(E)-ylidene]-(3-imidazol-1-ylmethyl-phenyl)-amine 
• 120107-92-8 [1-(4-Chloro-phenyl)-meth-(E)-ylidene]-(3-imidazol-1-ylmethyl-phenyl)-amine 
• 120108-23-8 N-(3-Imidazol-1-ylmethyl-phenyl)-2,4-dinitro-benzamide 
• 1114591-91-1 6-[(cyclopropylmethyl)(propyl)amino]-N-[3-(1H-imidazol-1-ylmethyl)phenyl]pyrimidine-4-carboxamide 
• 892393-40-7 (+)-N₁,N₄-di-(tert-butyloxycarbonyl)-N-[3-[(1H-imidazol-1-yl)-methyl]phenyl]-(2R)-piperazinecarboxamide 
• 892393-38-3 (-)-N₁,N₄-di-(tert-butyloxycarbonyl)-N-[3-[(1H-imidazol-1-yl)-methyl]phenyl]-(2S)-piperazinecarboxamide 
• 120123-75-3 (3-Imidazol-1-ylmethyl-phenyl)-(3,4,5-trimethoxy-benzyl)-amine 

Relevant articles and documents

Reversible photoresponsive activity of a carbonic anhydrase mimic

The carbonic anhydrase (CA) enzyme reversibly transforms carbon dioxide and water to a carbonate ion and a proton. Photoresponsive enzyme mimics, where the CA-activity can be turned on and off reversibly with light, have not been reported so far. We have designed an active site mimic that offers reversible control of the catalytic activity using light. Moreover, in the presence of a cationic polymer, we have demonstrated that the CA-activity was further enhanced by stabilizing the transition state with the cis-form of the enzyme mimic which can catalyze the hydration of gaseous CO2.

FARNESYL PROTEIN TRANSFERASE INHIBITORS AND METHODS FOR TREATING PROLIFERATIVE DISEASES

Disclosed are compounds of the Formula: (1.0) wherein the substituents are as defined herein. Also disclosed are uses of the compounds of formula 1.0 for the manufacture of a medicament for treating cancer and for inhibiting farnesyl protein transferase.

Research on anti-bacterial and anti-fungal agents II. Synthesis and anti-fungal activity of new (1H-imidazol-1-ylmethyl)benzenamine derivatives

The synthesis and in vivo and in vitro anti-fungal activities of new (1H-imidazol-1-ylmethyl)benzenamine derivatives are reported.Anti-microbial data in comparison with miconazole show that many compounds exhibit an interesting anti-mycotic activity.Keywo