1201079-10-8Relevant articles and documents
New and practical synthesis of N-(3-Cyano-7-ethoxy-4-oxo-1,4- dihydroquinolin-6-yl)acetamide
Ma, Wenpeng,Mao, Yongjun,Xie, Kai,Zhu, Qifeng,Zhang, Rongxia,Shen, Jingshan,Sun, Hongbin
, p. 866 - 868 (2014)
New and practical synthetic route of N-(3-cyano-7-ethoxy-4-oxo-1,4- dihydroquinolin-6-yl)acetamide (1) is described, through the cyclization of 2-aminophenyl-ethanone (12) with N,N-dimethylformamide dimethylacetal. The overall yield of 1 obtained from this process is 46% (five steps) with a purity of >99% (HPLC).