1201331-51-2Relevant academic research and scientific papers
Oxidative nucleophilic substitution: Transformation of alkylboronic derivatives
Cazorla, Clément,Métay, Estelle,Lemaire, Marc
, p. 8615 - 8621 (2011/11/30)
An efficient amidation reaction is described in this paper. Potassium alkyltrifluoroborate salts can be transforming to amides from nitriles in the presence of copper acetate and boron trifluoride. An extension of this reaction allowed the formation of amines, ethers, and C-C bond.
Ritter-type amidation of alkylboron derivatives with nitriles
Cazorla, Clément,Métay, Estelle,Andrioletti, Bruno,Lemaire, Marc
scheme or table, p. 6855 - 6857 (2010/05/03)
A mild and facile synthesis of amides from alkylboron compounds and nitriles promoted by copper acetate and BF3·OEt2 at room temperature is disclosed.
