120157-60-0

Usage

Uses

Used in Organic Chemistry:
2,3-O-(3-PENTYLIDENE)-D-GLYCERALDEHYDE is used as a building block for the synthesis of various chemical compounds due to its unique structure and reactivity, facilitating the creation of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2,3-O-(3-PENTYLIDENE)-D-GLYCERALDEHYDE is utilized as an intermediate in the production of pharmaceuticals, contributing to the development of new drugs.
Used in Agrochemical Production:
Similarly, in the agrochemical sector, 2,3-O-(3-PENTYLIDENE)-D-GLYCERALDEHYDE serves as an intermediate, playing a role in the synthesis of agrochemicals that are vital for agricultural applications.
Used in Chemical Synthesis Research:
2,3-O-(3-PENTYLIDENE)-D-GLYCERALDEHYDE is also applied in the field of chemical synthesis research, where its properties are explored for potential new applications and to enhance existing synthetic methodologies.

InChI:InChI=1/C8H14O3/c1-3-8(4-2)10-6-7(5-9)11-8/h5,7H,3-4,6H2,1-2H3/t7-/m0/s1

Upstream product

• 120157-59-7 1,2:5,6-di-O-(3-pentylidene)-D-mannitol 

Downstream Products

• 207302-95-2 (3R,4R,5R,6S)-5-Bromo-6-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-3-methoxy-4-methyl-tetrahydro-pyran-2-one 
• 207302-96-3 (3R,4S,5S)-5-{[(1S)-3,3-diethyl-2,4-dioxolanyl]bromomethyl}-3-methoxy-4-methyloxolan-2-one 
• 228243-79-6 (1R,2S)-1-((R)-2,2-Diethyl-[1,3]dioxolan-4-yl)-3-phenylsulfanyl-propane-1,2-diol 
• 227299-31-2 (S)-3-((S)-2,2-Diethyl-[1,3]dioxolan-4-yl)-1-phenylsulfanyl-but-3-en-2-ol 
• 228243-86-5 (S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-3-phenylsulfanyl-propan-1-one 
• 228243-80-9 (1S,2S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-3-phenylsulfanyl-propan-1-ol 
• 227299-40-3 tert-Butyl-[(S)-2-((S)-2,2-diethyl-[1,3]dioxolan-4-yl)-1-phenylsulfanylmethyl-allyloxy]-dimethyl-silane 
• 227299-32-3 [(S)-1-Benzenesulfinylmethyl-2-((S)-2,2-diethyl-[1,3]dioxolan-4-yl)-allyloxy]-tert-butyl-dimethyl-silane 
• 227299-33-4 Acetic acid (S)-2-(tert-butyl-dimethyl-silanyloxy)-3-((S)-2,2-diethyl-[1,3]dioxolan-4-yl)-1-phenylsulfanyl-but-3-enyl ester 
• 1612767-74-4 (S)-1-((R)-2,2-diethyl-1,3-dioxolan-4-yl)prop-2-ynyl 4-methylbenzenesulfonate 
• 152998-16-8 tert-Butyl-[(S)-3-((R)-2,2-diethyl-[1,3]dioxolan-4-yl)-3-methoxy-2,2-dimethyl-propoxy]-diphenyl-silane 
• 207303-18-2 (1S,2S,3R)-1-{[(1S)-3,3-diethyl-2,4-dioxolanyl]methyl}-3-methoxy-1-[(4-methoxyphenyl)methoxy]-2-methyl-4-(1,1,2,2-tetramethyl-1-silapropoxy)butane 
• 207303-05-7 (4R,5S,6S)-methyl 7-[(1S)-3,3-diethyl-2,4-dioxolanyl]-4-methoxy-6-[(4-methoxyphenyl)methoxy]-3,5-dimethylhept-2-enoate 

Relevant academic research and scientific papers

New approach for the stereoselective synthesis of (+)-epi-cytoxazone

The stereoselective total synthesis of (+)-epi-cytoxazone was performed satisfactorily in 8 steps, in 17percent overall yield, via a novel route from 2,3-O-(3-pentylidene)-(R)-glyceraldehyde. The bulky group alkene-ketal allowed intramolecular control of

Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility

A series of C-2 pyrroloquinoline analogs designed to improve aqueous solubility were examined for herpesvirus polymerase and antiviral activity. Several analogs were identified that maintained the antiviral activity of the previous development candidate against HCMV, HSV-1 and VZV, but with significantly improved aqueous solubility.

Synthetic studies toward amphidinolide A: Synthesis of fully functionalized subunits

A retrosynthetic breakdown of amphidinolide A affords four fragments A- D and illustrates the main synthetic challenges of this molecule. A concise stereoselective synthesis of the four appropriately functionalized subtargets is described.

2,3-O-(3-pentylidene)-D-glyceraldehyde and 2,3-O-(3-pentylidene)-L-glyceraldehyde: Convenient glyceraldehyde surrogates obtained via a novel periodate-based oxidation system

The synthesis of two novel glyceraldehyde surrogates, 2,3-O-(3-pentylidene)-D-glyceraldehyde (2) and 2,3-O-(3-pentylidene)-L-glyceraldehyde (3) is presented. Synthesis, handling and storage advantages of 2 and 3 over the conventionally employed 2,3-O-isopropylidene-D-glyceraldehyde (1) are discussed. The 3-pentanone-derived protecting group facilitates the extraction of product from aqueous oxidation solutions, while the 3-pentanone liberated on ketal deprotection can be efficiently removed at reduced pressures. The synthesis employs a buffered potassium periodate oxidation which offers significant advantages over sodium periodate in glycol cleavage reactions.