1201643-70-0

Basic information

• Product Name: 1-Phenylpyrazole-4-boronic acid
• Synonyms: 1-Phenylpyrazole-4-boronic acid;(1-Phenyl-1H-pyrazol-4-yl)boronic acid;1-Phenyl-1H-pyrazole-4-boronic acid
• CAS NO: 1201643-70-0
• Molecular Formula: C₉H₉BN₂O₂
• Molecular Weight: 187.99096
• Mol File: 1201643-70-0.mol

Chemical Properties

• Boiling Point: 393.1±34.0 °C(Predicted)
• Appearance: /
• Density: 1.20±0.1 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 7.44±0.10(Predicted)
• CAS DataBase Reference: 1-Phenylpyrazole-4-boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenylpyrazole-4-boronic acid(1201643-70-0)
• EPA Substance Registry System: 1-Phenylpyrazole-4-boronic acid(1201643-70-0)

Safety Data

• Hazardous Substances Data: 1201643-70-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-Phenylpyrazole-4-boronic acid is used as a key building block for the synthesis of various pharmaceuticals. Its boronic acid functionality allows for the formation of new carbon-carbon bonds through Suzuki coupling reactions, facilitating the creation of complex molecular structures with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Phenylpyrazole-4-boronic acid serves as an essential component in the development of new agrochemicals. Its reactivity in cross-coupling reactions enables the synthesis of novel compounds with pesticidal or herbicidal properties, contributing to the advancement of crop protection strategies.
Used in Organic Synthesis:
1-Phenylpyrazole-4-boronic acid is employed as a versatile reagent in organic synthesis. Its unique properties, including the phenylpyrazole moiety and boronic acid functionality, make it suitable for a wide range of applications, such as the formation of new carbon-carbon bonds and the synthesis of complex organic molecules with diverse functionalities.

Upstream product

• 15115-52-3 4-bromo-1-phenyl-1H-pyrazole 
• 1002334-12-4 1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 

Downstream Products

• 1603821-47-1 C₂₂H₂₀FN₅O₂S₂ 
• 1343459-80-2 5-(1-phenyl-1H-pyrazol-4-yl)-2-(1H-pyrazol-1-yl)pyrimidin-4-ol 
• 1343461-12-0 C₂₄H₂₀N₆O₂ 

Relevant articles and documents

PHOSPHATIDYLINOSITOL 3 KINASE INHIBITORS

Provided are compounds according to Formula (I), or stereoisomer, prodrug, polymorph, or pharmaceutically acceptable salt forms thereof, wherein X, Y, R1, R6 , R7, and R8 are as defined, which compounds are effective inhibitors of PI3-kinase and/or other medically and clinically relevant kinases. Also provided are pharmaceutical compositions and methods of using the compounds and compositions as PB -kinase and kinase inhibitors. More particularly, the compounds of the invention provide treatments and therapeutics for human diseases regulated by, or associated with, the activity of, PI3-kinases and/or protein kinases, or mutant or variant forms thereof.