1201646-88-9

Upstream product

• 1201643-75-5 (E)-5-bromo-2-((2-nitrovinyl)amino)benzoic acid 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 853908-50-6 6-bromo-3-nitroquinolin-4-ol 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1201646-94-7 C₂₉H₂₁N₅ 
• 1201646-95-8 C₃₀H₂₁N₅O₂ 
• 1201646-92-5 2-(4-((3'-amino[3,6'-biquinolin]-4'-yl)amino)phenyl)-2-methyl propanenitrile 
• 1201646-91-4 2-methyl-2-(4-((3'-nitro[3,6-biquinolin]-4'-yl)amino)-phenyl)propanenitrile 

Relevant academic research and scientific papers

PHOSPHATIDYLINOSITOL 3 KINASE INHIBITORS

Provided are compounds according to Formula (I), or stereoisomer, prodrug, polymorph, or pharmaceutically acceptable salt forms thereof, wherein X, Y, R1, R6 , R7, and R8 are as defined, which compounds are effective inhibitors of PI3-kinase and/or other medically and clinically relevant kinases. Also provided are pharmaceutical compositions and methods of using the compounds and compositions as PB -kinase and kinase inhibitors. More particularly, the compounds of the invention provide treatments and therapeutics for human diseases regulated by, or associated with, the activity of, PI3-kinases and/or protein kinases, or mutant or variant forms thereof.