4-Hydroxy-3-nitroquinoline-6-boronic acid pinacol ester

Base Information

Chemical Name:4-Hydroxy-3-nitroquinoline-6-boronic acid pinacol ester
CAS No.:1201646-88-9
Molecular Formula:C15H17BN2O5
Molecular Weight:316.12
Hs Code.:
Mol file:1201646-88-9.mol

Synonyms:1201646-88-9;4-Hydroxy-3-nitroquinoline-6-boronic acid pinacol ester;3-nitro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-quinolin-4-one;6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3-NITROQUINOLIN-4-OL;SCHEMBL12266657;MFCD18383953;AKOS025395280

Suppliers and Price of 4-Hydroxy-3-nitroquinoline-6-boronic acid pinacol ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

TRC
4-Hydroxy-3-nitroquinoline-6-boronicAcidPinacolEster
100mg
$ 130.00

Total 0 raw suppliers

Chemical Property of 4-Hydroxy-3-nitroquinoline-6-boronic acid pinacol ester

Chemical Property:

PSA：97.40000
LogP:2.67100
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:316.1230518
Heavy Atom Count:23
Complexity:553

Purity/Quality:: 4-Hydroxy-3-nitroquinoline-6-boronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)NC=C(C3=O)[N+](=O)[O-]

Technology Process of 4-Hydroxy-3-nitroquinoline-6-boronic acid pinacol ester

There total 3 articles about 4-Hydroxy-3-nitroquinoline-6-boronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 853908-50-6
6-bromo-3-nitroquinolin-4-ol

: 73183-34-3
bis(pinacol)diborane

: 1201646-88-9
C₁₅H₁₇BN₂O₅

Guidance literature:: With potassium acetate; bis-triphenylphosphine-palladium(II) chloride; In dimethyl sulfoxide; at 80 ℃; Inert atmosphere;

Reference yield:

: 1201643-75-5
(E)-5-bromo-2-((2-nitrovinyl)amino)benzoic acid

: 1201646-88-9
C₁₅H₁₇BN₂O₅

Guidance literature:: Multi-step reaction with 2 steps

1: potassium acetate / acetic anhydride / 1.5 h / 120 °C

2: potassium acetate / bis-triphenylphosphine-palladium(II) chloride / dimethyl sulfoxide / 80 °C / Inert atmosphere

With potassium acetate; bis-triphenylphosphine-palladium(II) chloride; In acetic anhydride; dimethyl sulfoxide;

Reference yield:

: 5794-88-7
5-Bromo-2-aminobenzoic acid

: 1201646-88-9
C₁₅H₁₇BN₂O₅

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / water / 18 h / 20 °C

2: potassium acetate / acetic anhydride / 1.5 h / 120 °C

3: potassium acetate / bis-triphenylphosphine-palladium(II) chloride / dimethyl sulfoxide / 80 °C / Inert atmosphere

With hydrogenchloride; potassium acetate; bis-triphenylphosphine-palladium(II) chloride; In water; acetic anhydride; dimethyl sulfoxide;