1201683-27-3Relevant academic research and scientific papers
Synthesis of 2-arylthio arylcyanamides from 2-iodoaryl isothiocyanates: Via a one-pot three-component reaction
Pinapati, Srinivasarao,Mandapati, Usharani,Tamminana, Ramana,Rudraraju, Rameshraju
supporting information, p. 8711 - 8713 (2017/08/29)
A one-pot three-component reaction has been described for the synthesis of substituted 2-arylthio arylcyanamides. A cheap and readily available iron source was used as a catalyst for this reaction. Consecutive addition and domino C-S cross-coupling reacti
The synthesis of 2-(Arylthio)arylcyanamides via copper-catalyzed domino intermolecular c-s cross-coupling reaction of 2-aminobenzothiazoles with aryl iodides
Shao, Yin-Lin,Zhang, Xiao-Hong,Han, Jiang-Sheng,Zhong, Ping
, p. 1137 - 1146 (2013/09/23)
A series of 2-(arylthio)arylcyanamide derivatives were obtained in excellent yields via a copper-catalyzed domino C-S cross-coupling of 2-aminobenzothiazoles with aryl iodides. This reaction occurred via an intermolecular C-S bond formation, associated with C-S bond cleavage, followed by an intermolecular S-arylation under ligand-free conditions. Their structures were unambiguously determined by the analytic tools, such as HRMS, 1H, and 13C NMR analysis.
Copper(I)-catalyzed cascade synthesis of 2-arylsulfanyl-arylcyanamides
Sahoo, Santosh K.,Jamir, Latonglila,Guin, Srimanta,Patel, Bhisma K.
experimental part, p. 2538 - 2548 (2010/12/29)
We have developed a ligand-assisted copper(I)-catalyzed two sequential heteroarylation sequence. An intramolecular S-arylation is followed by an intermolecular N-arylation leading to the direct synthesis of N-aryl-2-aminobenzothiazoles. In most cases however, the 2-arylsulfanyl- arylcyanamide was the major product obtained via an intramolecular C-S bond formation, associated with C-S bond breakage, followed by an intermolecular S-arylation. The selectivity of this ligand-assisted reaction is quite different as compared to that of ligand-free reactions and the rates are much faster giving good yields of products. Various cyanamides can be prepared in excellent yields from their corresponding 1-substituted thioureas with or without the assistance of a ligand with a catalytic quantity of copper(I).
Copper-catalyzed domino intra- And intermodular C-S cross-coupling reactions: Synthesis of 2-(Arylthio)arylcyanamides
Ramana, Tamminana,Saha, Prasenjit,Das, Manas,Punniyamurthy, Tharmalingam
supporting information; experimental part, p. 84 - 87 (2010/03/03)
Chemical Equation Presented One-pot synthesis of 2-(arylthio)arylcyanamides is accomplished using cheap and air-stable CuSO 4·5H2O as a catalyst by domino intra- and intermolecular C-S cross-coupling reactions of 2-(iodoaryl)thioureas with aryl iodides under ligand-free conditions
