66644-79-9

Basic information

• Product Name: 2-BROMO-4-METHYLPHENYLTHIOUREA
• Synonyms: 1-(2-BROMO-4-METHYLPHENYL)-2-THIOUREA;2-BROMO-4-METHYLPHENYLTHIOUREA;1-(2-Bromo-4-methylphenyl)thiourea;N-(2-Bromo-4-methyl)phenylthiourea, 98%
• CAS NO: 66644-79-9
• Molecular Formula: C₈H₉BrN₂S
• Molecular Weight: 245.14
• Mol File: 66644-79-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 174-176°C
• Appearance: /
• BRN: 2719238
• CAS DataBase Reference: 2-BROMO-4-METHYLPHENYLTHIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-METHYLPHENYLTHIOUREA(66644-79-9)
• EPA Substance Registry System: 2-BROMO-4-METHYLPHENYLTHIOUREA(66644-79-9)

Safety Data

• Hazard Codes: Xi
• Statements: 22-36
• Safety Statements: 22-36/37
• RIDADR: 2811
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 66644-79-9(Hazardous Substances Data)

Usage

Description

2-BROMO-4-METHYLPHENYLTHIOUREA is a white solid chemical compound that belongs to the class of thioureas. It is used in organic synthesis and pharmaceutical research, and has been studied for its potential use in the treatment of thyroid disorders and cancer. It has also been used as a reagent in the synthesis of various organic compounds. 2-BROMO-4-METHYLPHENYLTHIOUREA has shown promise as a versatile building block for the development of new pharmaceuticals and bioactive compounds. However, it is important to handle this compound with care, as it may pose hazards to human health and the environment.

Uses

Used in Pharmaceutical Research:
2-BROMO-4-METHYLPHENYLTHIOUREA is used as a research compound for the development of new pharmaceuticals and bioactive compounds. Its versatile structure makes it a promising building block for creating novel therapeutic agents.
Used in Organic Synthesis:
2-BROMO-4-METHYLPHENYLTHIOUREA is used as a reagent in the synthesis of various organic compounds, contributing to the development of new chemical entities with potential applications in various industries.
Used in Thyroid Disorder Treatment:
2-BROMO-4-METHYLPHENYLTHIOUREA has been studied for its potential use in the treatment of thyroid disorders, indicating its possible application in the medical field for managing such conditions.
Used in Cancer Treatment Research:
2-BROMO-4-METHYLPHENYLTHIOUREA has been investigated for its potential role in cancer treatment, suggesting that it could be utilized in oncology research to develop new cancer therapies.

Upstream product

• 19241-39-5 (2-bromo-4-methylphenyl)isothiocyanate 
• 58655-25-7 C₆H₁₅N*C₈H₈BrNS₂ 
• 13194-71-3 2-bromo-4-methyl-aniline; hydrochloride 
• 583-68-6 2-bromo-p-toluidine 
• 446831-64-7 1-benzoyl-3-(2-bromo-4-methyl-phenyl)-thiourea 

Downstream Products

• 1201683-15-9 2-(4-aminophenylthio)-4-methylphenylcyanamide 
• 1260248-77-8 2-(2-nitrophenylthio)-4-methylphenylcyanamide 
• 85063-58-7 6-methyl-N-(2-nitrophenyl)benzo[d]thiazol-2-amine 
• 1201683-27-3 2-(4-methylphenylthio)-4-methylphenylcyanamide 
• 1201683-11-5 4-methyl-2-(phenylthio)phenylcyanamide 
• 1201683-18-2 2-(4-nitrophenylthio)-4-methylphenylcyanamide 
• 1208070-80-7 2-bromo-4-methylphenylcyanamide 
• 109317-29-5 (2-Bromo-4-methyl-phenyl)-(4,5,6,7-tetrahydro-benzothiazol-2-yl)-amine 
• 109317-47-7 2-(2-Bromo-4-methyl-phenylamino)-5,5-dimethyl-5,6-dihydro-4H-benzothiazol-7-one; hydrobromide 

Relevant articles and documents

Environmentally benign one-pot synthesis of cyanamides from dithiocarbamates using I2 and H2O2

An environmentally benign reaction is devised for the synthesis of cyanamides from dithiocarbamate salts using iodine and H2O 2. Taylor & Francis Group, LLC.

Synthesis of some new 2,4-disubstituted thiazoles as possible antibacterial and anti-inflammatory agents

A series of arylthioureas (1), aromatic aldehyde thiosemicarbazones (2) and 5-aryl-2-furfuraldehyde thiosemicarbazones (3) were condensed with 2,4-dichloro-5-fluorophenacyl bromide to yield respective arylaminothiazoles, arylidene/5-aryl-2-furfurylidene hydrazinothiazoles (4). The newly synthesized compounds were characterized by IR, 1H-NMR and mass spectral studies. These compounds were also screened for their antibacterial and anti-inflammatory activities. Two of the newly synthesized compounds showed anti-inflammatory activity comparable with that of Ibuprofen.