1201798-97-1

Basic information

• Product Name: Propanoic Acid, 2,2-DiMethyl-, [5-(2,4-Dichloropyrido[2,3-D]PyriMidin-7-Yl)-2-Methoxyphenyl]Methyl Ester
• CAS NO: 1201798-97-1
• Molecular Formula: C20H19Cl2N3O3
• Molecular Weight: 420.295
• Mol File: 1201798-97-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 506.5±50.0 °C(Predicted)
• Density: 1.318±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Propanoic Acid, 2,2-DiMethyl-, [5-(2,4-Dichloropyrido[2,3-D]PyriMidin-7-Yl)-2-Methoxyphenyl]Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic Acid, 2,2-DiMethyl-, [5-(2,4-Dichloropyrido[2,3-D]PyriMidin-7-Yl)-2-Methoxyphenyl]Methyl Ester(1201798-97-1)
• EPA Substance Registry System: Propanoic Acid, 2,2-DiMethyl-, [5-(2,4-Dichloropyrido[2,3-D]PyriMidin-7-Yl)-2-Methoxyphenyl]Methyl Ester(1201798-97-1)

Safety Data

• Hazardous Substances Data: 1201798-97-1(Hazardous Substances Data)

Upstream product

• 1201798-96-0 5-(2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-7-yl)-2-methoxybenzyl pivalate 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 62581-82-2 1-[3-(chloromethyl)-4-methoxyphenyl]-1-ethanone 
• 1201798-95-9 (E)-5-(3-(dimethylamino)acryl)-2-methoxybenzyl pivalate 
• 1201798-94-8 5-acetyl-2-methoxybenzyl pivalate 

Downstream Products

• 1201798-98-2 5-{2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl}-2-methoxybenzyl pivalate 

Relevant articles and documents

Pyridopyrimidine Or Pyrimidopyrimidine Compound, Prepration Method, Pharmaceutical Composition, And Use Thereof

The present invention belongs to the field of pharmaceutical Chemistry. In particular, the present invention relates to a pyridopyrimidine or pyrimidopyrimidine compound as represented by general formula (I), or an isomer thereof or a pharmaceutically acceptable salt, ester, prodrug or solvate thereof, a preparation method, a pharmaceutical composition and uses thereof in preparing a mTOR inhibitor. As a mTOR inhibitor, the compound or the pharmaceutical composition thereof can be used for treating a disease or condition due to PI3K-AKT-mTOR signalling pathway malfunction.