120182-60-7

Upstream product

• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 

Downstream Products

• 85613-47-4 (S)-2-phenyl-3-<2-(3,4-dimethoxyphenyl)ethyl>-5-(hydroxymethyl)oxazolidine p-toluenesulfonate 
• 85648-13-1 (S)-2-amino>-2-hydroxypropoxy>phenyl>-4-(2-thienyl)imidazole 
• 66781-20-2 {(S)-3-[2-(3,4-Dimethoxy-phenyl)-ethyl]-2-phenyl-oxazolidin-5-yl}-methanol 
• 85613-42-9 (S)-4-<3-<<2-(3,4-dimethoxyphenyl)ethyl>amino>-2-hydroxypropoxy>benzaldehyde 
• 85648-10-8 (S)-3-<<2-(3,4-dimethoxyphenyl)ethyl>amino>-1,2-propanediol 

Relevant academic research and scientific papers

Process for preparing alkoxyalkyl-idenehydrazinopyridazine derivatives

A process for preparing a compound of the formula (4): is described wherein R3 and R4 are both hydrogen or together are =CR1R2, where R1 is hydrogen or C1-3alkyl and R2 is C1-3alkyl, carboxy or phenyl,which comprises reduc

β1-Selective adrenoceptor antagonists: Examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class

A series of 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazoles is described. The compounds were investigated in vitro for β-adrenoceptor antagonism, and several examples were found to be selective for the β1-adrenoceptor. The structure-activity relationship exhibited by this series of compounds is discussed. (S)-2-[p-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-2-hydroxypropoxy]phenyl] -4-(2-thienyl)imidazole [(S)-13] was over 100 times more selective than atenolol for the β1-adrenergic receptor and has been selected for in-depth studies.