120187-98-6

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 78513-07-2 (-)-(2S,3R)-2,3-epoxy-4-(benzyloxy)-1-butanol 
• 87172-27-8 cis-4-benzyloxy-2,3-epoxy-1-butanol 
• 84621-89-6 trans-4-(benzyloxy)-2,3-epoxy-1-butanol 

Downstream Products

• 120567-35-3 ((1S,2R)-1,2-Bis-benzyloxymethyl-but-3-enyloxy)-tert-butyl-dimethyl-silane 
• 120188-03-6 [(2R,3S,4S)-4-Benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-oxetan-2-yl]-methanol 
• 120211-02-1 1-[(2R,3R,4S)-4-Benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-oxetan-2-yl]-ethanone 
• 120188-08-1 {(R)-2-[(S)-2-Benzyloxy-1-(4-methoxy-benzyloxy)-ethyl]-but-3-enyloxy}-tert-butyl-dimethyl-silane 
• 120188-02-5 Methanesulfonic acid (1S,2R,3S)-1-allyloxymethyl-4-benzyloxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-hydroxy-butyl ester 
• 120188-01-4 (2S,3S,4S)-1-Allyloxy-5-benzyloxy-3-(tert-butyl-dimethyl-silanyloxymethyl)-4-(4-methoxy-benzyloxy)-pentan-2-ol 
• 120188-01-4 (2R,3S,4S)-1-Allyloxy-5-benzyloxy-3-(tert-butyl-dimethyl-silanyloxymethyl)-4-(4-methoxy-benzyloxy)-pentan-2-ol 
• 113368-83-5 (2S,3R)-1-Benzyloxy-3-benzyloxymethyl-pent-4-en-2-ol 
• 132121-56-3 (2S,3R)-1-Benzyloxy-3-benzyloxymethyl-4,5-epoxypentan-2-ol 
• 132121-59-6 (4S,5S)-4,5-Bis-benzyloxymethyl-tetrahydro-furan-3-ol 
• 120188-00-3 (2S,3R)-1-Benzyloxy-3-(4-methoxy-benzyloxymethyl)-pent-4-en-2-ol 
• 120187-99-7 (R)-2-[(S)-2-Benzyloxy-1-(4-methoxy-benzyloxy)-ethyl]-but-3-en-1-ol 

Relevant academic research and scientific papers

First enantioselective non-biological synthesis of asymmetrised tris(hydroxymethyl)methane (THYM*) and bis(hydroxymethyl)acetaldehyde (BHYMA*)

An asymmetric synthesis of a chiral non-racemic (O-benzyl, O′-silyl) derivative of the latent C3v-symmetric tris(hydroxymethyl)methane (THYM*) and of the bis(hydroxymethyl)acetaldehyde (BHYMA*) in 6 steps, 38% overall yield and 7 steps, 36% ove

An improved, practical synthesis of the derivatives of 1-O-acetyl-2-deoxy-2-hydroxymethyl-D-erythrooxetanose, a key sugar moiety for the synthesis of oxetanosyl-N-glycoside

Intramolecular cyclization of the cis-epoxy-alcohol (6) with KOH in aq.DMSO provided predominantly the oxetane compound (7), which on oxidation followed by Baeyer-Villiger reaction gave 1-O-acetyl-D-erythrooxetanoses.