120190-41-2

Upstream product

• 120190-36-5 (2R,5S,1'R,2'S,3'R)-2-(1'-acetoxy-2'3'-epoxy-3'-phenyl-prop-1'-yl)-2,5-dihydro-5-isopropyl-3,6-dimethoxy-pyrazine 
• 104-55-2 3-phenyl-propenal 
• 107384-38-3 (E)-(S)-1-((2R,5S)-5-Isopropyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-3-phenyl-prop-2-en-1-ol 
• 120190-32-1 (2R,5S,1'R,2'R 3'R)-2-(2',3'-epoxy-1'-hydroxy-3'-phenyl-prop-1'-yl)-2,5-dihydro-5-isopropyl-3,6-dimethoxy-pyrazine 

Relevant academic research and scientific papers

ASYMMETRIC SYNTHESIS VIA HETEROCYCLIC INTERMEDIATES - XXXIX. ASYMMETRTIC SYNTHESIS OF (ENANTIOMERICALLY AND DIASTEREOMERICALLY VIRTUALLY PURE) METHYL 2-AMINO-4,5-EPOXY-3-HYDROXY-ALKANOATES AND METHYL 2-AMINO-3-HYDROXY-4,5-METHYLENE-ALKANOATES BY THE BISLA

α,β-Unsaturated aldehydes react with the titanated bislactim ether 6 of cyclo-(L-val-gly) to give the (2R,1'S)-syn-addition products of type 8.With TBHP (catalyzed by Ti(OiPr)4 with and without (+)- or (-)-DET) these furnish the epoxides 10 or 11 with 1',