1201938-24-0Relevant articles and documents
Efficient synthesis of 2-aryl-2: H -indazoles by base-catalyzed benzyl C-H deprotonation and cyclization
Gao, Wen-Xia,Jin, Guo-Qing,Liu, Miao-Chang,Wu, Hua-Yue,Zhou, Yun-Bing
, p. 14617 - 14620 (2020/12/02)
A straightforward and efficient method for the preparation of 2-aryl-2H-indazoles from ortho-alkyl substituted azoxybenzenes is presented. The reaction proceeds through base-catalyzed benzyl C-H deprotonation and cyclization to afford 2-aryl-2H-indazoles
Room-Temperature, Metal-Free, and One-Pot Preparation of 2H-Indazoles through a Mills Reaction and Cyclization Sequence
Kondo, Masaru,Takizawa, Shinobu,Jiang, Yuzhao,Sasai, Hiroaki
supporting information, p. 9866 - 9869 (2019/07/10)
The Mills reaction and cyclization of readily available 2-aminobenzyl alcohols and nitrosobenzenes using thionyl bromide provided 2H-indazoles in up to 88 % yields. In the metal-free process, acetic acid played a crucial role for the both Mills reaction and cyclization. A brominated 2H-indazole could also be obtained through the one-pot sequence.
Synthesis of 2 H-indazoles by the [3 + 2] dipolar cycloaddition of sydnones with arynes
Fang, Yuesi,Wu, Chunrui,Larock, Richard C.,Shi, Feng
, p. 8840 - 8851 (2012/01/02)
A rapid and efficient synthesis of 2H-indazoles has been developed using a [3 + 2] dipolar cycloaddition of sydnones and arynes. A series of 2H-indazoles have been prepared in good to excellent yields using this protocol, and subsequent Pd-catalyzed coupl
