120200-50-2

Basic information

• Product Name: methyl 4,6-O-benzylidene-2,3-di-O-methyl-α-D-mannopyranoside
• Synonyms: methyl 4,6-O-benzylidene-2,3-di-O-methyl-α-D-mannopyranoside
• CAS NO: 120200-50-2
• Molecular Weight: 310.347
• Mol File: 120200-50-2.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: methyl 4,6-O-benzylidene-2,3-di-O-methyl-α-D-mannopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4,6-O-benzylidene-2,3-di-O-methyl-α-D-mannopyranoside(120200-50-2)
• EPA Substance Registry System: methyl 4,6-O-benzylidene-2,3-di-O-methyl-α-D-mannopyranoside(120200-50-2)

Safety Data

• Hazardous Substances Data: 120200-50-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 6752-76-7 methyl 4,6-O-benzylidene-2-O-methyl-β-D-idopyranoside 
• 129831-96-5 methyl 4,6-O-(S)-benzylidene-3-O-methyl-β-D-idopyranoside 
• 74560-62-6 methyl 4,6-O-(S)-benzylidene-2-methyl-α-D-idopyranoside 
• 74560-63-7 methyl 4,6-O-(S)-benzylidene-3-methyl-α-D-idopyranoside 
• 3162-96-7 methyl 4,6-O-benzylidene-α-D-glucopyranoside 
• 77-78-1 dimethyl sulfate 
• 74560-56-8 methyl 4,6-O-(S)-benzylidene-α-D-idopyranoside 
• 287191-51-9 methyl 4,6-O-benzylidene-β-D-idopyranoside 
• 64552-06-3 methyl 4,6-O-benzylidene-α-D-galactopyranoside 
• 74-88-4 methyl iodide 
• 3162-96-7 4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside 
• 120408-72-2 Methyl 2,3-anhydro-4,6-O-(phenylmethylene)-β-D-allopyranoside 

Downstream Products

• 106220-89-7 methyl 6-O-benzyl-2,3-di-O-methyl-α-D-glucopyranoside 
• 83075-53-0 methyl 4-O-benzyl-2,3-di-O-methyl-α-D-glucopyranoside 
• 56543-17-0 methyl 4-O-benzoyl-6-bromo-6-deoxy-2,3-di-O-methyl-α-D-glucopyranoside 
• 108223-99-0 methyl 4-O-benzyl-6-bromo-6-deoxy-4-O-(methoxyethoxymethyl)-2,3-di-O-methyl-α-D-glucopyranoside 
• 10227-29-9 methyl 2,3-di-O-methyl-α-D-glucopyranoside 
• 1064194-70-2 [(2R,3R,4S,5R,6S)-4,5,6-Trimethoxy-3-(phenyl-phenylsulfanyl-methoxy)-tetrahydro-pyran-2-yl]-methanol 
• 51517-51-2 methyl 6-O-benzoyl-2,3-di-O-methyl-α-D-glucopyranoside 
• 56586-54-0 methyl 4,6-O-benzylidene-2,3-di-O-methyl-α-D-glucopyranoside 
• 82159-70-4 methyl 4-O-benzoyl-6-deoxy-2,3-di-O-methyl-α-D-glucopyranoside 
• 196801-96-4 methyl 4-O-benzyl-2,3-di-O-methyl-6-O-triphenylmethyl-α-D-glucopyranoside 
• 51016-10-5 methyl 2,3-di-O-methyl-6-O-(triphenylmethyl)-α-D-glucopyranoside 
• 27299-03-2 methyl 2,3-di-O-methyl-6-O-triphenylmethyl-α-D-galactopyranoside 
• 51433-19-3 methyl 4-O-benzyl-2,3-di-O-methyl-α-D-galactopyranoside 
• 74334-92-2 methyl 4-O-benzyl-2,3,6-tri-O-methyl-α-D-galactopyranoside 

Relevant articles and documents

Establishment of Guidelines for the Control of Glycosylation Reactions and Intermediates by Quantitative Assessment of Reactivity

Stereocontrolled chemical glycosylation remains a major challenge despite vast efforts reported over many decades and so far still mainly relies on trial and error. Now it is shown that the relative reactivity value (RRV) of thioglycosides is an indicator for revealing stereoselectivities according to four types of acceptors. Mechanistic studies show that the reaction is dominated by two distinct intermediates: glycosyl triflates and glycosyl halides from N-halosuccinimide (NXS)/TfOH. The formation of glycosyl halide is highly correlated with the production of α-glycoside. These findings enable glycosylation reactions to be foreseen by using RRVs as an α/β-selectivity indicator and guidelines and rules to be developed for stereocontrolled glycosylation.

Compositions and methods for modification of biomolecules

The present invention provides modified cycloalkyne compounds; and method of use of such compounds in modifying biomolecules. The present invention features a cycloaddition reaction that can be carried out under physiological conditions. In general, the invention involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).

USE OF CO2 FOR THE SYNTHESIS OF CYCLIC GLYCOCARBONATES AND LINEAR POLYGLYCOCARBONATES BY POLYCONDENSATION FROM GLYCANS

Provided herein are methods for synthesizing cyclic carbonates, glycocarbonates, and polyglycocarbonates by reacting polyol glycans with carbon dioxide. Synthesis can include selective polycondensation of polyol glycan hydroxyl moieties.