120225-75-4

Basic information

• Product Name: 2-CHLORO-2',3'-O-ISOPROPYLIDENEADENOSINE-5'-N-ETHYLCARBOXAMIDE
• Synonyms: 2-CHLORO-2',3'-O-ISOPROPYLIDENEADENOSINE-5'-N-ETHYLCARBOXAMIDE;2-Chloro-23O-isopropylideneadenosine-5N-ethylcaboxamide;1-(6-AMino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-Methylethylidene)-β-D-ribofuranuronaMide;6-(6-aMino-2-chloro-9H-purin-9-yl)-N-ethyl-2,2-diMethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxaMide;(3aS,4S,6R,6aR)-6-(6-aMino-2-chloro-9H-purin-9-yl)-N-ethyl-2,2-diMethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxaMide;(3AS,4S,6R,6aR)-6-(6-amino-2-chloro-9H-purin-9-yl)-N-ethyl-2,2-dimethyltetrahydrofuro[3,4-d][1;2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine
• CAS NO: 120225-75-4
• Molecular Formula: C₁₅H₁₉ClN₆O₄
• Molecular Weight: 382.8
• Product Categories: Bases & Related Reagents;Inhibitors;Nucleotides
• Mol File: 120225-75-4.mol

Chemical Properties

• Melting Point: 210-212°C
• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: DMSO, MeOH, DMF; 50 mg/L gives a clear colourless solution
• CAS DataBase Reference: 2-CHLORO-2',3'-O-ISOPROPYLIDENEADENOSINE-5'-N-ETHYLCARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-2',3'-O-ISOPROPYLIDENEADENOSINE-5'-N-ETHYLCARBOXAMIDE(120225-75-4)
• EPA Substance Registry System: 2-CHLORO-2',3'-O-ISOPROPYLIDENEADENOSINE-5'-N-ETHYLCARBOXAMIDE(120225-75-4)

Safety Data

• Hazardous Substances Data: 120225-75-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
2-CHLORO-2',3'-O-ISOPROPYLIDENEADENOSINE-5'-N-ETHYLCARBOXAMIDE is used as a potent selective adenosine receptor agonist for its ability to selectively target adenosine receptors, which can be beneficial in the development of drugs targeting specific conditions related to adenosine receptor activity.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-CHLORO-2',3'-O-ISOPROPYLIDENEADENOSINE-5'-N-ETHYLCARBOXAMIDE is used to prepare photoreactive 2-phenethylamine derivatives. This application takes advantage of the compound's unique chemical properties to create new molecules with potential uses in various industries.
Used in Research and Development:
2-CHLORO-2',3'-O-ISOPROPYLIDENEADENOSINE-5'-N-ETHYLCARBOXAMIDE is also utilized in research and development, particularly in the study of adenosine receptor function and the development of new drugs targeting these receptors. Its selective agonist properties make it a valuable tool for understanding the role of adenosine receptors in various biological processes and diseases.

Upstream product

• 75-04-7 ethylamine 
• 146-77-0 2-Chloroadenosine 
• 72209-19-9 2-chloro-2',3'-O-isopropylideneadenosine-5'-carboxylic acid 
• 24639-06-3 ((3aR,4R,6R,6aR)-6-(6-amino-2-chloro-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol 

Downstream Products

• 127258-43-9 (4-{2-[6-Amino-9-((3aR,4R,6S,6aS)-6-ethylcarbamoyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-9H-purin-2-ylamino]-ethyl}-phenoxy)-acetic acid tert-butyl ester 
• 127258-36-0 (3aS,4S,6R,6aR)-6-(6-Amino-2-benzylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid ethylamide 
• 1433011-20-1 (2S,3S,4R,5R)-5-[6-amino-2-(4-azidophenethylamino)-9H-purin-9-yl]-N-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide 
• 1433011-00-7 (3aS,4S,6R,6aR)-6-[6-amino-2-(4-azidophenethylamino)-9H-purin-9-yl]-N-ethyl-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxamide 
• 1433011-07-4 (3aS,4S,6R,6aR)-6-[6-amino-2-(4-benzoylphenethylamino)-9H-purin-9-yl]-N-ethyl-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxamide 
• 1365619-15-3 (3aS,4S,6R,6aR)-6-[6-amino-2-(4-bromophenethylamino)-9H-purin-9-yl]-N-ethyl-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxamide 
• 127258-46-2 2-<<4-(2-carbomethoxyetyl)phenethyl>amino>adenosine-5'-N-ethylcarboxamide hydrochloride 
• 127258-42-8 (4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-ylamino]-ethyl}-phenoxy)-acetic acid; hydrochloride 
• 124431-80-7 2-p-(2-carboxyethyl)phenethylamino-5'-N-ethylcarboxamidoadenosine hydrochloride 
• 127258-44-0 (4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-ylamino]-ethyl}-phenyl)-acetic acid; hydrochloride 
• 127258-37-1 (2S,3S,4R,5R)-5-{6-Amino-2-[2-(4-chloro-phenyl)-ethylamino]-purin-9-yl}-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide; hydrochloride 
• 127258-40-6 (2S,3S,4R,5R)-5-[6-Amino-2-(methyl-phenethyl-amino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide; hydrochloride 
• 127258-35-9 (2S,3S,4R,5R)-5-(6-Amino-2-benzylamino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide; hydrochloride 
• 120225-58-3 (2S,3S,4R,5R)-5-{6-Amino-2-[2-(4-fluoro-phenyl)-ethylamino]-purin-9-yl}-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide 

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