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Upstream product

• 622-33-3 N-benzyloxyamine 
• 4358-87-6 (RS)-methyl mandelate 
• 20698-91-3 (R)-methyl mandelate 

Relevant academic research and scientific papers

Solution and solid phase synthesis of 5-alkoxyhydantoin libraries with a three-fold functional diversity

A general model for the synthesis of 5-alkoxyhydantoins in solution and on solid support is described. A library of fifty discrete 5-alkoxyhydantoins with three functional group variations was prepared.

Interconversion of (R) and (S)-α-hydroxy esters: precursors of (S) and (R)-O-benzyl-α-hydroxylamino acid esters of high optical purity.

(R)- and (S)-α-hydroxy esters 5 are interconverted via their triflates 6 in high chemical as well as optical yields by reaction with dimethylformamide.The same triflates are efficiently converted into N-hydroxy-α-amino acid derivatives 7 of high optical purity.