120238-38-2Relevant academic research and scientific papers
A New and Convenient Synthesis of N-Substituted Perhydroazepines from Adipaldehyde and Primary Amines with Tetracarbonylhydridoferrate, HFe(CO)4-, as a Selective Reducing Agent
Shim, Sang Chul,Doh, Chil Hoon,Kim, Tae Jeong,Lee, Hak Ki,Kim, Ki Doo
, p. 1383 - 1385 (2007/10/02)
Ethanolic tetracarbonylhydridoferrate combined with adipaldehyde is very efficient for the selective transformation of an amino group into perhydroazepine.A large variety of both aliphatic and aromatic amines react with adipaldehyde in the presence of tetracarbonylhydridoferrate at room temperature and carbon monoxide to give the corresponding N-alkyl- and N-arylperhydroazepines in good to excellent yields.
