1202647-32-2

Upstream product

• 790663-45-5 cyclopropyl-(3-methoxy-2-methyl-benzyl)-amine 
• 851314-48-2 8-{4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl}-5-aza-spiro[2.5]oct-7-ene-5,7-dicarboxylic acid 5-tert-butyl ester 7-methyl ester 
• 143306-64-3 tert-butyl 8-oxo-5-azaspiro[2.5]octane-5-carboxylate 
• 851314-35-7 8-oxo-5-aza-spiro[2.5]octane-5,7-dicarboxylic acid 5-tert-butyl ester 7-methyl ester 
• 851314-38-0 8-trifluoromethanesulfonyloxy-5-aza-spiro[2.5]oct-7-ene-5,7-dicarboxylic acid 5-tert-butyl ester 7-methyl ester 
• 1223461-35-5 2-[3-(4-bromophenyl)propoxy]-3-chloro-1,4-difluorobenzene 
• 1202647-16-2 C₂₁H₂₄BClF₂O₃ 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 

Downstream Products

• 1349024-62-9 C₃₅H₃₇ClF₂N₂O₃ 

Relevant academic research and scientific papers

New classes of potent and bioavailable human renin inhibitors

New classes of de novo designed renin inhibitors are reported. Some of these compounds display excellent in vitro and in vivo activities toward human renin in a TGR model. The synthesis of these new types of mono- and bicyclic scaffolds are reported, and properties of selected compounds discussed.