143306-64-3 Usage
Description
Tert-butyl 8-oxo-5-azaspiro[2.5]octane-5-carboxylate is a synthetic compound with a complex molecular structure, characterized by its 8-oxo-5-azaspiro[2.5]octane core and a carboxylate group attached to a tert-butyl moiety. tert-butyl 8-oxo-5-azaspiro[2.5]octane-5-carboxylate is known for its potential applications in the pharmaceutical industry, particularly in the development of enzyme inhibitors.
Uses
Used in Pharmaceutical Industry:
Tert-butyl 8-oxo-5-azaspiro[2.5]octane-5-carboxylate is used as a reagent for the preparation of 2,3-oxidosqualene cyclase inhibitors. These inhibitors are important in the development of drugs targeting various diseases, as they can modulate the activity of the enzyme 2,3-oxidosqualene cyclase, which plays a crucial role in the biosynthesis of steroids and other related compounds. By inhibiting this enzyme, it is possible to disrupt the synthesis of these compounds, which can be beneficial in treating certain conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 143306-64-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,3,0 and 6 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 143306-64:
(8*1)+(7*4)+(6*3)+(5*3)+(4*0)+(3*6)+(2*6)+(1*4)=103
103 % 10 = 3
So 143306-64-3 is a valid CAS Registry Number.
143306-64-3Relevant articles and documents
BICYCLIC PIPERIDINE AND PIPERAZINE DERIVATIVES AS GPCR MODULATORS FOR THE TREATMENT OF OBESITY, DIABETES AND OTHER METABOLIC DISORDERS
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Page/Page column 64-65, (2010/11/03)
The present invention relates to Bicyclic Piperidine and Piperazine Derivatives, compositions comprising a Bicyclic Piperidine and Piperazine Derivative, and methods of using the Bicyclic Piperidine and Piperazine Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of a GPCR in a patient.
AMIDE-SUBSTITUTED ARYL PIPERIDINES
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Page/Page column 75, (2008/12/05)
Amide-substituted aryl piperidines derivatives of the following Formulas are provided:(Formulas), in which the variables are as described herein. Such compounds may be used to modulate calcitonin gene-related peptide (CGRP) receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions responsive to CGRP modulation in humans, domesticated companion animals and livestock animals, including headache, such as migraine. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such compounds for receptor localization studies and various in vitro assays.