120276-48-4Relevant articles and documents
Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity
Bruneau,Delvare,Edwards,McMillan
, p. 1028 - 1036 (2007/10/02)
Since the hypothetical mechanisms of hydroperoxydation of arachidonic acid by, respectively, 5-lipoxygenase (5-LPO) and cyclooxygenase (CO) involve a redox cycle, a compound which reduces 5-LPO and CO to their inactive state would give a nonselective inhi