1202778-95-7

Basic information

• Product Name: cyano-di(3-phenyl-prop-1-yl)acetic acid methyl ester
• Synonyms: cyano-di(3-phenyl-prop-1-yl)acetic acid methyl ester
• CAS NO: 1202778-95-7
• Molecular Weight: 335.446
• Mol File: 1202778-95-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: cyano-di(3-phenyl-prop-1-yl)acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: cyano-di(3-phenyl-prop-1-yl)acetic acid methyl ester(1202778-95-7)
• EPA Substance Registry System: cyano-di(3-phenyl-prop-1-yl)acetic acid methyl ester(1202778-95-7)

Safety Data

• Hazardous Substances Data: 1202778-95-7(Hazardous Substances Data)

Upstream product

• 637-59-2 1-Bromo-3-phenylpropane 
• 1025483-41-3 methyl 2-cyano-5-phenylpentanoate 
• 105-34-0 methyl 2-cyanoacetate 

Downstream Products

• 1365564-13-1 C₂₂H₂₉NO₂ 
• 1202779-20-1 C₂₆H₃₅NO₄ 
• 1202779-08-5 C₂₇H₃₇NO₄ 

Relevant articles and documents

THERAPEUTIC PEPTIDES

The present invention provides a peptide, peptidomimetic or amino acid derivative having a net positive charge of at least +2 and incorporating a disubstituted β amino acid, each of the substituting groups in the β amino acid, which may be the same or dif

Antimicrobial activity of small β-peptidomimetics based on the pharmacophore model of short cationic antimicrobial peptides

We have synthesized a series of small β-peptidomimetics (Mw 2,2-amino acid coupled to a C-terminal L-arginine amide residue. By varying the lipophilic side-chains of the β2,2-amino acids, we obtained a series of highly potent β-peptidomimetics with high enzymatic stability against α-chymotrypsin and a general low toxicity against human erythrocytes. The most potent β-peptidomimetics displayed minimal inhibitory concentrations of 2.1-7.2 μM against Staphylococcus aureus, methicillin resistant Staphylococcus aureus (MRSA), methicillin resistant Staphylococcus epidermidis (MRSE), and Escherichia coli. Small amphipathic β-peptidomimetics may be a promising class of antimicrobial agents by means of having a similar range of potency and selectivity as larger cationic antimicrobial peptides in addition to improved enzymatic stability and lower costs of production.