1202914-01-9

Basic information

• Product Name: 2,2-diphenyl-2-(N-4-methoxyphenylamino)acetonitrile
• Synonyms: 2,2-diphenyl-2-(N-4-methoxyphenylamino)acetonitrile
• CAS NO: 1202914-01-9
• Molecular Weight: 314.387
• Mol File: 1202914-01-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,2-diphenyl-2-(N-4-methoxyphenylamino)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-diphenyl-2-(N-4-methoxyphenylamino)acetonitrile(1202914-01-9)
• EPA Substance Registry System: 2,2-diphenyl-2-(N-4-methoxyphenylamino)acetonitrile(1202914-01-9)

Safety Data

• Hazardous Substances Data: 1202914-01-9(Hazardous Substances Data)

Upstream product

• 119-61-9 benzophenone 
• 630-18-2 tert-butyl isocyanide 
• 104-94-9 4-methoxy-aniline 
• 7677-24-9 trimethylsilyl cyanide 
• 42834-19-5 N-(4-methoxyphenyl)-1,1-diphenylmethanimine 

Relevant articles and documents

Magnetic solid sulfonic acid decorated with hydrophobic regulators: A combinatorial and magnetically separable catalyst for the synthesis of α-aminonitriles

A three-component, Strecker reaction of a series of aldehydes or ketones, amines, and trimethylsilyl cyanide for the synthesis of α-aminonitriles in the presence of a catalytic amount of a magnetic solid sulfonic acid catalyst, Fe3O4@SiO2@Me&Et-PhSO3H under solvent-free conditions have been investigated. This catalyst, with a combination of hydrophobicity and acidity on the Fe3O 4@SiO2 core-shell of the magnetic nanobeads, as well as its water-resistant property, enabled easy mass transfer and catalytic activity in the Strecker reaction. The catalyst was easily separated by an external magnet and the recovered catalyst was reused in 6 successive reaction cycles without any significant loss of activity.

Solvent-free three component Strecker reaction of ketones using highly recyclable and hydrophobic sulfonic acid based nanoreactors

An efficient and environmentally benign system was developed for the one-pot three-component Strecker reaction of ketones under solvent-free conditions, with the use of a highly recoverable SBA-15 supported sulfonic acid. Also findings concerning the effects of functionalized inert groups and silica backbone pore size on substrate scope, catalytic activity and recycling behavior of the catalysts were briefly discussed. The simple experimental and product isolation procedure accompanied by easy recovery and reusability of the catalyst could be considered as attractive features of this new protocol which will hopefully develop a clean strategy for the synthesis of α-amino nitriles. The Royal Society of Chemistry 2009.