120312-10-9Relevant academic research and scientific papers
A stereochemical surprise at the late stage of the synthesis of fully N-differentiated heparin oligosaccharides containing amino, acetamido, and N-sulfonate groups
Lohman, Gregory J. S.,Seeberger, Peter H.
, p. 4081 - 4093 (2007/10/03)
The glucosamine residues in heparin-like glycosaminoglycans have been found to exist as amines, acetamides, and N-sulfonates. To develop a completely general, modular synthesis of heparin, three degrees of orthogonal nitrogen protection are required. Repo
Glycosyl Imidates, 41. - 6-O-Benzyl-Protected Muramic Acid as Glycosyl Acceptor. - Synthesis of the GlcNAc-β-(1->4)MurNAc Disaccharide
Termin, Andreas,Schmidt, Richard R.
, p. 789 - 796 (2007/10/02)
The α-trichloroacetimidates 1 and 2 as glucosamine donors afford with the 6-O-benzyl-protected muramic acid 6a as acceptor the β-connected disaccharides 14 and 15, respectively, in high yields.Compound 14 furnishes by cleavage of the TBDMS group, transfor
