120312-72-3Relevant academic research and scientific papers
Copper/Manganese Cocatalyzed Oxidative Coupling of Vinylarenes with Ketones
Lan, Xing-Wang,Wang, Nai-Xing,Zhang, Wei,Wen, Jia-Long,Bai, Cui-Bing,Xing, Yalan,Li, Yi-He
, p. 4460 - 4463 (2015)
A novel copper/manganese cocatalyzed direct oxidative coupling of terminal vinylarenes with ketones via C(sp3)-H bond functionalization following C-C bond formation has been developed using tert-butyl hydroperoxide as the radical initiator. Various ketones underwent a free-radical addition of terminal vinylarenes to give the corresponding 1,4-dicarbonyl products with excellent regioselectivity and efficiency through one step. A possible reaction mechanism has been proposed.
Carbon-Carbon Bond Formation in Reactions of PhIO*HBF4/Silyl Enol Ether Adduct with Alkenes or Silyl Enol Ethers
Zhdankin, Viktor V.,Mullikin, Michelle,Tykwinski, Rik,Berglund, Bruce,Caple, Ronald,et al.
, p. 2605 - 2608 (2007/10/02)
A new method for generation of reactive α-ketomethyl aryliodonium intermediates from silyl enol ethers and PhIO*HBF4 has been developed.Reactions of PhIO*HBF4/silyl enol ether adduct with alkenes (1-hexene, cyclohexene, α-methylstyrene, allyltrimethylsilane, 2,3-dimethyl-2-butene) yielded products of allylic alkylation or (in case of 2,3-dimethyl-2-butene) a substituted dihydrofuran.Reactions of adducts from PhIO/HBF4 and silyl enol ethers of acetophone, p-chloroacetophenone, p-methylacetophenone, and p-nitroacetophenone with various silyl enol ethers led to unsymmetrical 1,4-butanediones as major products.
