120329-64-8

Upstream product

• 2938-98-9 (R)-2-methylbutane-1,4-diol 
• 98-88-4 benzoyl chloride 
• 369365-14-0 dimethyl (2S,3R)-3-methyl-2-O-tosylmalate 
• 931-23-7 5-Hydroxy-3-methyl-5H-furan-2-one 
• 40834-42-2 5-hydroxy-4-methyl-5H-furan-2-one 
• 120263-07-2 (5S)-5-<(+)-menthyloxy>-4-methyl-2(5H)furanone 
• 120262-98-8 (5R)-5-(l-menthyloxy)-3-methyl-2(5H)-furanone 
• 22644-27-5 (R)-methylsuccinic acid dimethyl ester 
• 93-97-0 benzoic acid anhydride 
• 1592891-16-1 (E)-4-(4-methoxyphenyl)pent-3-en-2-yl acetate 
• 72824-04-5 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 120263-02-7 (4R,5S)-5-((1S,2R,5S)-2-Isopropyl-5-methyl-cyclohexyloxy)-4-methyl-dihydro-furan-2-one 
• 120263-03-8 (3R,5R)-5-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-3-methyl-dihydro-furan-2-one 
• 369365-18-4 dimethyl (2RS,3R)-2-chloro-3-methylsuccinate 

Relevant academic research and scientific papers

Catalytic stereospecific allyl-allyl cross-coupling of internal allyl electrophiles with allylB(pin)

Application of internal electrophiles in catalytic stereospecific allyl-allyl cross-coupling enable the rapid construction of multisubstituted 1,5-dienes, including those with all carbon quaternary centers. Compounds with minimal steric differentiation ca

A new asymmetric synthesis of (R)-3-methylpyrrolidine alkaloids starting from (S)-malic acid

Diastereoselective methylation of dimethyl (S)-malate (8) followed by two three-step reductive dehydroxylation procedures afforded dimethyl (R)-2-methylsuccinate (16) in 80.2% and 84.7% ee respectively, the later was further transformed into the natural enantiomers of ant venom alkaloids (R)-leptothoracine (1) and (R)-3-methyl-N-(2-phenylethyl)pyrrolidine (2) and (3R, 2'S)-3-methyl-N-(2-methylbutyl)pyrrolidine (3).