120340-35-4

Usage

Structure

Ester derivative of 1,4-Diazabicyclo[2.2.2]octane-2-methanol

Functional Groups

Ester, Amine

Type of Compound

Organic compound

Application

a. Catalyst in various organic reactions
b. Base in the synthesis of pharmaceuticals and agrochemicals
c. Curing agent for epoxy resins

Reactivity

High reactivity and selectivity

Importance

Important tool in the field of organic chemistry

Safety Precautions

Handle with caution due to potential health risks

Upstream product

• 29924-68-3 methyl 1,4-diazabicyclo<2.2.2>octane-2-carboxylate 
• 76950-41-9 2-benzyloxymethyl-1,4-diazabicyclo<2.2.2>octane dihydrochloride 
• 69491-40-3 1,4-diazabicyclo<2.2.2>octene-2-carboxylic acid dihydrobromide 
• 76950-43-1 2-hydroxymethyl-1,4-diazabicyclo<2.2.2>octane 
• 108-24-7 acetic anhydride 

Relevant academic research and scientific papers

Diazabicycloalkanes with nitrogen atoms in the nodal positions. 5. Synthesis and some reactions of 2-hydroxymethyl-1,4-diazabicyclo [2.2.2]octane

2-Hydroxymethyl-1,4-diazabicyclo[2.2.2]octane was synthesized by reduction of 1,4-diazabicyclo[2.2.2]octane-2-carboxylic acid or its methyl ester with lithium aluminum hydride in tetrahydrofuran and by hydrolysis or hydrogenation of 2-benzyloxymethyl-1,4-diazabicyclo[2.2.2]octane. Depending on the conditions, 2-hydroxymethyl-1,4-diazabicyclo[2.2.2]octane reacts with methyl iodide to give primarily either a bisquaternary or a monoquaternary derivative. The latter is the only product in its alkylation with methyl esters of benzoic and caproic acids.