76950-43-1Relevant academic research and scientific papers
Method for synthesizing hydroxylalkyltriethylenediamine compound
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Paragraph 0015-0018, (2019/10/01)
The invention relates to a method for synthesizing a hydroxylalkyltriethylenediamine compound. The method comprises the steps of taking solid phosphorylated graphene (PGO) as a catalyst, adding a monosubstituted dihydroxylalkyl piperazine derivative and any of polar solvents with a dielectric constant greater than 10 into a reaction vessel, heating the temperature of the reaction vessel to 100 DEGC to 300 DEG C in a nitrogen gas atmosphere, carrying out a reaction for 1 to 5 hours with stirring under a reaction vessel pressure of 1 MPa to 10 MPa, cooling the temperature of the reaction vesselto 30 DEG C to 60 DEG C, then, subjecting the catalyst and a reaction solution to centrifugation, and subjecting the reaction solution to rectification under vacuum, thereby obtaining the product, i.e., the hydroxylalkyltriethylenediamine compound represented by a formula (I) shown in the description. According to the method, the process is simple, and the catalyst can be cyclically regenerated.In a synthesis process for 2-hydroxymethyl triethylenediamine, the conversion ratio of a reactant, i.e., dihydroxylalkyl piperazine can reach 95% or more, and the selectivity of the product, i.e., the2-hydroxymethyl triethylenediamine can reach 90% or more.
Method for preparing methylol triethylene diamine
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Paragraph 0023; 0024, (2019/01/16)
The invention relates to a method for preparing methylol triethylene diamine by using piperazine and 2,3-dihalopropanol as raw materials: with the formula in the description below.
PRODUCTION METHOD FOR BICYCLIC AMINE COMPOUND
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Paragraph 0050; 0051; 0056, (2019/01/06)
PROBLEM TO BE SOLVED: To provide a production method for obtaining bicyclic amine compounds with high reaction yield. SOLUTION: The method includes subjecting a hydroxyl group-containing cyclic amine compound of a formula (1) to intramolecular dehydration in a gas phase in the presence of a solid catalyst containing alkaline earth metal phosphate and alkali metal salt [in the formula (1), R1 to R8 each independently represent a hydrogen atom, a C1 to 4 alkyl group, a hydroxy group, a hydroxymethyl group, or a C1 to 4 alkoxy group; X represents a carbon atom or a nitrogen atom; Y represents an alkyl group, a hydroxy group, a C1 to 4 hydroxyalkyl group, or a C1 to 4 aminoalkyl group]. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT
METHOD FOR PRODUCING BICYCLIC AMINES
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Paragraph 0064; 0068, (2018/06/12)
PROBLEM TO BE SOLVED: To provide a method for producing bicyclic amines with improved yield thereof. SOLUTION: Provided is a method for producing bicyclic amine compounds represented by formula (1), which are hydroxyalkyltriethylenediamines, by subjecting a raw material composition to intramolecular dehydration in vapor phase in the presence of a solid catalyst, where a mixture of N-dihydroxypropylpiperazines and N,N'-bis(dihydroxypropyl)piperazines is used as the raw material composition and an inorganic oxide represented by formula (4) is used as the solid catalyst [R1 to R8 are each independently H, a C1-4 alkyl group, a hydroxy group, a hydroxymethyl group, or a C1-4 alkoxy group]. AlaMbPcOd (4) [M is an alkali metal or an alkaline earth metal; P is phosphorus; 0.001≤b/a≤0.5 (molar ratio); 0.01≤c/a≤0.5 (molar ratio); and d is a number which depends on the bonding states of respective atoms]. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT
METHOD FOR PRODUCING CYCLIC AMINES
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Paragraph 0032; 0038, (2018/09/25)
PROBLEM TO BE SOLVED: To provide a method for efficiently producing cyclic amines. SOLUTION: The present invention provides a method for producing cyclic amines represented by formula (2), including subjecting alkanolamines to cyclodehydration in the presence of a solid catalyst containing at least one selected from titanium oxide, silicon oxide, and zirconium oxide (R3-R10 independently represent H, C1-4 alkyl, a hydroxy group, hydroxymethyl or C1-4 alkoxy; X is C or N; Y is alkyl, a hydroxy group, C1-4 hydroxyalkyl or C1-4 aminoalkyl). SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT
Method for continuous production of 2 - hydroxymethyl three ethylene diamine
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Paragraph 0033; 0034; 0035, (2017/08/25)
The invention discloses a method of producing 2-hydroxymethyl triethylenediamine continuously. The method comprises the following steps: feeding materials containing a hydroxyethyl piperazine derivative into a tubular reactor which is filled with a solid catalyst continuously, carrying out reaction on the materials in the tubular reactor, collecting, and treating to obtain 2-hydroxymethyl triethylenediamine. 1-hydroxyethyl-3-hydroxymethyl piperazine or 1-hydroxyethyl-2-hydroxymethyl piperazine and N-(beta-hydroxymethyl-beta-hydroxyethyl)piperazine or N-(alpha-hydroxymethyl-beta-hydroxyethyl)piperazine or a mixture thereof are used as the raw materials, the metal oxide of strontium, barium, magnesium, iron, nickel and/or zinc is used as the catalyst, and 2-hydroxymethyl triethylenediamine is prepared through intramolecular dehydration and cyclization. The method disclosed by the invention is simple and is suitable for industrial production.
METHOD FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE HAVING IMPROVED HUE
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Paragraph 0048, (2017/12/12)
PROBLEM TO BE SOLVED: To provide a production method which makes it possible to improve the hue of a cyclic alkanolamine such as a hydroxyalkyltriethylenediamine and efficiently obtain a high-purity bicyclic compound. SOLUTION: A method for producing the bicyclic diamine includes bringing a crude hydroxyalkyltriethylenediamine reaction liquid comprising a hydroxyalkyltriethylenediamine represented by formula (1) into contact with oxygen at 110-170°C and then distilling and purifying it (R1-R10 independently represent H, a C1-4 alkyl group or a C1-4 hydroxyalkyl group). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT
METHOD FOR PRODUCING BICYCLIC AMINE COMPOUND
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Paragraph 0049; 0054, (2017/11/15)
PROBLEM TO BE SOLVED: To provide a stable production method for a bicyclic amine compound that inhibits the generation of by-products in the production of a bicyclic amine. SOLUTION: The present invention provides a method for producing a bicyclic amine compound which employs a catalyst comprising an inorganic support and an alkali metal phosphate, and further comprising alkaline earth metal hydroxide and/or hydroxyapatite in an amount of 1.5 wt.% or more and less than 15 wt.% relative to the inorganic support. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPO&INPIT
CURING AGENT FOR USE IN PRODUCTION OF POLYUREA RESIN, AND POLYUREA RESIN PRODUCTION METHOD USING SAME
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Paragraph 0043-0044, (2017/04/11)
To provide a curing agent for producing a polyurea resin, which is capable of thermal compression molding, which will not cause odor and toxicity or environmental problems at the time of molding or of products, which has favorable adhesive strength, and which hardly causes pollution of other materials, and a method for producing a polyurea resin using it. A curing agent for producing a polyurea resin, which comprises at least one diamine compound selected from the group consisting of compounds each represented by the following formula (1): wherein n is 0 or 1, and R is a hydroxy group or hydroxyalkyl group having 0 to 2 carbon atoms, and at least one amine compound selected from the group consisting of N,N-dimethylaminoethanol, N,N-dimethylaminoisopropanol and N,N-dimethyl-N′,N′-di(2-hydroxypropyl)propylenediamine.
The method of manufacturing the amine compound Bicylic
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Paragraph 0063-0065, (2017/04/19)
PROBLEM TO BE SOLVED: To provide a method for simply obtaining a bicyclic amine compound at high yield and for suppressing by-product tar contents that may obstruct the continuous production. SOLUTION: The compound indicated by a formula (1) is subjected to intramolecular dehydration in a gas phase under the presence of a solid catalyst to produce the bicyclic amine compound indicated by a formula (2). In the formula (1), R1-R8each independently represents a hydrogen atom, a 1-4C alkyl group, a hydroxy group, a hydroxymethyl group or a 1-4C alkoxy group; X represents a carbon atom or a nitrogen atom; and Y represents a hydrogen atom, an alkyl group, a hydroxy group or a 1-4C hydroxyalkyl group. In the formula (2), R1-R8, X and Y are defined in the same manner as above. COPYRIGHT: (C)2012,JPOandINPIT
