120342-30-5

Basic information

• Product Name: ethyl 6-bromo-5-methoxy-2-methyl-1H-indole-3-carboxylate
• Synonyms: ethyl 6-bromo-5-methoxy-2-methyl-1H-indole-3-carboxylate
• CAS NO: 120342-30-5
• Molecular Formula: C13H14BrNO3
• Molecular Weight: 312.15916
• Mol File: 120342-30-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 6-bromo-5-methoxy-2-methyl-1H-indole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6-bromo-5-methoxy-2-methyl-1H-indole-3-carboxylate(120342-30-5)
• EPA Substance Registry System: ethyl 6-bromo-5-methoxy-2-methyl-1H-indole-3-carboxylate(120342-30-5)

Safety Data

• Hazardous Substances Data: 120342-30-5(Hazardous Substances Data)

Upstream product

• 34572-31-1 ethyl 5-methoxy-2-methyl-1H-indole-3-carboxylate 

Downstream Products

• 120342-32-7 1-(2,3-Epoxypropyl)-2-methyl-3-ethoxycarbonyl-5-methoxy-6-bromoindole 

Relevant articles and documents

Additive-Free Copper(I)-Mediated Synthesis of 5- or 6-Brominated 2-Aryl-1 H-Indole-3-Carboxylates from α,α-Dibromo β-Iminoesters

Additive-free copper(I)-bromide-mediated radical cyclization reactions of α,α-dibromo β-iminoesters were investigated, enabling the synthesis of a series of 5- or 6-brominated 2-aryl-1H-indole-3-carboxylates in moderate to good yields. The mechanistic study showed that (i) the bromine atom originated from the substrates and (ii) the bromination might be related to a 3-bromo-3H indole intermediate via an electrophilic bromine atom transfer. Furthermore, the practicality of this method was demonstrated by gram-scale synthesis and the potential for product derivatization toward other valuable multisubstituted indoles.