34572-31-1

Usage

Derivative of indole

The compound is derived from the naturally occurring compound indole, which is a bicyclic aromatic organic compound.

Used in synthesis of pharmaceuticals and agrochemicals

The compound is commonly used as a building block or intermediate in the synthesis of various pharmaceuticals and agrochemicals.

More soluble in organic solvents

The presence of the ethyl ester group makes the compound more soluble in organic solvents, which can be beneficial for certain chemical reactions and applications.

Enhanced stability

The ethyl ester group also enhances the stability of the compound, making it more resistant to degradation and breakdown.

Unique properties from substituent

The 5-methoxy-2-methyl substituent on the indole ring imparts unique properties to the compound, making it useful in drug discovery and development.

Potential applications in pharmaceutical industry

The compound has potential applications in the pharmaceutical industry for the treatment of various diseases and disorders.

Upstream product

• 141-97-9 ethyl acetoacetate 
• 33240-23-2 ethyl 3-((4-methoxyphenyl)amino)but-2-enoate 
• 626-34-6 ethyl aminocrotonate 
• 106-51-4 p-benzoquinone 
• 7598-91-6 ethyl 5-hydroxy-2-methylindole-3-carboxylate 
• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 
• 85160-90-3 ethyl 1-benzenesulphonyl-2-bromomethyl-5-methoxyindole-3-carboxylate 
• 143582-27-8 ethyl 1-phenylsulfonyl-5-methoxy-2-phenylsulfonylmethylindole-3-carboxylate 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 80191-95-3 Ethyl 1-benzenesulphonyl-5-methoxy-2-methylindole-3-carboxylate 
• 120342-30-5 2-Methyl-3-ethoxycarbonyl-5-methoxy-6-bromoindole 
• 120342-32-7 1-(2,3-Epoxypropyl)-2-methyl-3-ethoxycarbonyl-5-methoxy-6-bromoindole 
• 1076-74-0 5-methoxy-2-methyl-1H-indole 

Relevant academic research and scientific papers

Facile access to polysubstituted indoles via a cascade Cu-catalyzed arylation - Condensation process

(Chemical Equation Presented) CuI/L-proline-catalyzed cross-coupling of 2-halotrifluoroacetanilides with β-keto esters and amides followed by in situ acidic hydrolysis delivered 2,3-disubstituted indoles. The halides bearing a strong electron-withdrawing

Base-promoted, CBr4-mediated tandem bromination/intramolecular Friedel-Crafts alkylation ofN-aryl enamines: a facile access to 1H- And 3H-indoles

Described here is a general and highly efficient method for the synthesis of 1H- and 3H-indoles. In the presence of CBr4and a suitable base, the cyclization ofN-aryl enamines proceeds with high efficiency. Unlike previous intramolecular cross d

MUSCARINIC ACETYLCHOLINE RECEPTOR SUBTYPE 4 ANTAGONISTS IN THE TREATMENT OF ANEMIA

This disclosure generally relates to treating anemias. More specifically, the disclosure relates to use of muscarinic acetylcholine receptor subtype 4 antagonists, such as small molecule compounds, to promote self-renewal of burst forming unit erythroid (BFU-E) cells and treat anemias.

Substituted indoles as alpha-1 agonists

This invention relates to compounds which are alpha-1 receptor agonists, preferably alpha-1A/L receptor agonists, and which are represented by Formula I: wherein m, A, X, Y, R1, R2, R3, R4 and R5 are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, methods for their use as therapeutic agents, and methods of preparation thereof.

Synthesis of 2-alkylindoles via sulfones

Elaboration of carbanions generated from 1-phenylsulfonyl-2(phenylsulfonylmethyl)indole derivatives followed by removal of the C-phenylsulfonyl group by Raney nickel affords 2-alkylindoles.