120349-75-9

Basic information

• Product Name: BOC-O-BENZYL-L-SERINOL
• Synonyms: (R)-(+)-3-BENZYLOXY-2-(TERT-BUTOXYCARBONYLAMINO)-1-PROPANOL;N-BOC-L-SER(BZL)-OL;N-BOC-L-SER(BZL)-OL-N-BOC-(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL;N-BOC-(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL;N-ALPHA-T-BOC-O-BENZYL-L-SERINOL;N-T-BUTOXYCARBONYL-O-BENZYL-L-SERINOL;BOC-SERINOL(BZL);BOC-SER(BZL)-OL
• CAS NO: 120349-75-9
• Molecular Formula: C₁₅H₂₃NO₄
• Molecular Weight: 281.35
• Product Categories: Amino Acids
• Mol File: 120349-75-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 66-69 °C(lit.)
• Appearance: /
• CAS DataBase Reference: BOC-O-BENZYL-L-SERINOL(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-O-BENZYL-L-SERINOL(120349-75-9)
• EPA Substance Registry System: BOC-O-BENZYL-L-SERINOL(120349-75-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 120349-75-9(Hazardous Substances Data)

Usage

General Description

BOC-O-BENZYL-L-SERINOL is a synthetic organic compound commonly used as a building block in the synthesis of pharmaceuticals and other bioactive molecules. It is an amino alcohol derivative with a benzyl group and a BOC (tert-butoxycarbonyl) protecting group attached to the serinol backbone. BOC-O-BENZYL-L-SERINOL can be used as a starting material for the preparation of peptide and non-peptide compounds, as well as in the development of new drugs, due to its potential biological activity and capacity for structural modification. Its versatile and valuable properties make it a useful tool in medicinal chemistry and drug discovery research.

Upstream product

• 17355-19-0 methyl (R)-2-amino-3-(4-methoxyphenyl)propanoate 
• 94790-24-6 (2R)-tert-butoxycarbonylamino-3-(4-methoxyphenyl)propionic acid methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 478623-19-7 ethyl (1R,4R,5R)-5-[1-(tert-butoxycarbonyl)amino-2-(4-methoxyphenyl)ethyl]-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 478623-18-6 ethyl (2R,3S,4R)-4-(tert-butoxycarbonyl)amino-2,3-dihydroxy-5-(4-methoxyphenyl)pentanoate 
• 478623-20-0 (1R,4R,5R)-1-[N-(tert-butoxycarbonyl)]-1-(5-bromomethyl-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(4-methoxyphenyl)ethan-1-amine 
• 478623-17-5 ethyl (2E,4R)-4-(tert-butoxycarbonyl)amino-5-(4-methoxyphenyl)pent-2-enoate 
• 228396-55-2 (1R,4S,5R)-5-[1-(tert-butoxycarbonyl)amino-2-(4-methoxyphenyl)ethyl]-2,2-dimethyl-1,3-dioxolan-4-ylmethanol 
• 27958-06-1 (2R,3S,4S)-3,4-dihydroxy-2-(4-methoxybenzyl)pyrrolidine 
• 139183-60-1 [(R)-1-Formyl-2-(4-methoxy-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 120349-77-1 (Z)-(R)-4-tert-Butoxycarbonylamino-5-(4-methoxy-phenyl)-pent-2-enoic acid methyl ester 
• 120349-78-2 [(Z)-(R)-4-Hydroxy-1-(4-methoxy-benzyl)-but-2-enyl]-carbamic acid tert-butyl ester 
• 120349-79-3 (R)-2-(4-Methoxy-benzyl)-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester 
• 21399-39-3 (R)-2-(p-methoxyphenyl)methy-2,5-dihydropyrrole 

Relevant articles and documents

An efficient synthesis of (-)-deacetylanisomycin starting from D-tyrosine1

The antibiotic (-)-deacetylanisomycin was synthesized starting from D-tyrosine using Sharpless asymmetric dihydroxylation as a key reaction.